低水平激光治疗慢性牙周炎患者牙周炎症及牙根刮治术后愈合的临床生化研究。

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-04-21 DOI:10.4103/jpbs.jpbs_1930_24
Rakhi Soni, Mimoh Sharma, Tabassum, Renu Singh, Bipin K Yadav, Rajesh K Thakur
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引用次数: 0

摘要

目的:本研究的目的是确定低水平激光治疗(LLLT)后刮治和根规划(SRP)对慢性牙周炎引起的炎症性牙周组织的影响。方法:该研究涉及28例56个部位,几乎两侧对称,口袋深度适中。这些网站被随机分成两组。第一组单独给予SRP,第二组给予带有LLLT的SRP。除了记录临床参数[斑块指数(PI)、沟出血指数(SBI)和探查袋深度(PPD)]外,还在基线、3 ~ 4周和6 ~ 7周时采集GCF样本。两组患者在LLLT的最后一天(SRP后7天)进行视觉模拟评分(VAS)。然后将所有GCF样品送去进行TGF-β1和PGE2生化分析。结果:本研究显示,经SRP治疗后,I组患者PI、SBI、PPD、VAS评分、GCF中PGE2、TGF- β1水平均显著降低。同样,在II组,接受LLLT和SRP,所有临床和生化参数均显着下降。组间比较,GCF中PI、SBI、TGF-β1水平差异无统计学意义。然而,两组在PPD、VAS评分和PGE2水平结果上存在显著差异。结论:我们的研究表明,LLLT作为SRP的辅助治疗可能有效减轻炎症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Low Level Laser Therapy on Periodontal Inflammation and Healing after Scaling and Root Planing in Chronic Periodontitis Patients - A Clinico Biochemical Study.

Aim: The aim of this study was to determine how Low-level laser therapy (LLLT) post- Scaling and root planning (SRP) affected the inflammatory periodontal tissue caused by chronic periodontitis.

Methodology: The study involved 56 sites in 28 patients with almost bilaterally symmetrical moderate pocket depths. The sites were split into two groups at random. SRP was administered alone to Group I, while SRP with LLLT were administered to Group II. In addition to recording the clinical parameters [plaque index (PI), sulcus bleeding index (SBI), and probing pocket depth (PPD)], GCF sample was taken at baseline, 3 to 4 weeks, and 6 to 7 weeks from baseline. The visual analogue scale (VAS) was scored for both groups on the final day of LLLT, which was 7 days following SRP. All GCF samples were then sent for TGF-β1 and PGE2 biochemical analysis.

Results: This study demonstrated a significant reduction in PI, SBI, PPD, VAS score, PGE2 and TGF- β1 level in GCF in group I after SRP. Similarly in group II, which received LLLT with SRP, showed a significant decrease in all clinical and biochemical parameters. Intergroup comparison showed no significant difference in PI, SBI, TGF-β1 levels in the GCF. However, there was a significant difference in PPD, VAS score, and PGE2 level results.

Conclusion: Our study concluded that LLLT may be effective in reducing inflammation when used as an adjunct to SRP.

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