中国老年人肌肉减少症与跌倒之间的关系:来自中国健康与退休纵向研究的发现。

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
PLoS ONE Pub Date : 2025-06-12 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0326193
Chunhua Yang, Tengfei Ye, Yan Gao
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引用次数: 0

摘要

跌倒已经成为老年人死亡的一个重要因素。对于肌肉减少症是否会成为老年人跌倒的危险因素,我们知之甚少。本研究旨在根据2019年亚洲肌肉减少症工作组(AWGS 2019)更新的诊断指南,评估中国老年人肌肉减少症与跌倒之间的关系。我们使用的数据来自2011年基线和2015年中国健康与退休纵向研究(CHARLS)的随访调查。本研究通过横断面分析考察了肌肉减少症状态与跌倒之间的关系。采用Cox比例风险回归模型研究肌肉减少症对后续跌倒的影响,并报告风险比(HR)。共有5337名年龄在60岁以上的参与者(51.3%男性;平均年龄(67.6±6.3))从CHARLS 2011纳入本分析。研究显示,与未患肌肉减少症组相比,可能患有肌肉减少症和肌肉减少症组的跌倒发生率明显更高,分别为15.8%、19.4%和24%。运用Logistic回归研究肌肉减少症与跌倒之间的关系。两种可能的肌肉减少症(OR: 1.22, 95% CI: 1.03-1.45)和肌肉减少症(OR: 1.64, 95% CI: 1.23-2.19)均与较高的跌倒几率呈正相关
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Association between sarcopenia and falls in Chinese older adults: Findings from the China health and retirement longitudinal study.

Association between sarcopenia and falls in Chinese older adults: Findings from the China health and retirement longitudinal study.

Association between sarcopenia and falls in Chinese older adults: Findings from the China health and retirement longitudinal study.

Association between sarcopenia and falls in Chinese older adults: Findings from the China health and retirement longitudinal study.

Falling has become a significant factor in the mortality of elderly people. Little is known about whether sarcopenia can be a risk factor for falls in older adults. This study aims to assess the association between sarcopenia and falls among older Chinese according to the updated diagnostic guidelines of the Asian Working Group on Sarcopenia 2019 (AWGS 2019). We used data from the 2011 baseline and 2015 follow-up survey of the China Health and Retirement Longitudinal Study (CHARLS). This study examined the relationship between sarcopenia status and falls through cross-sectional analysis. Cox proportional hazards regression models were conducted to investigate the effect of sarcopenia status on subsequent falls, with the report of hazard ratio (HR). A total of 5,337 participants aged at least 60 years (51.3% men; mean age 67.6 ± 6.3) were enrolled in this analysis from the CHARLS 2011. The study revealed that the prevalence of falls was significantly higher in the possible sarcopenia and sarcopenia groups compared to the no sarcopenia group, with rates of 15.8%, 19.4%, and 24%, respectively. Logistic regression was utilized to investigate the association between sarcopenia and falls. Both possible sarcopenia (OR: 1.22, 95% CI: 1.03-1.45) and sarcopenia (OR: 1.64, 95% CI: 1.23-2.19) were positively associated with higher odds of falls (all p < 0.05). During the 4 years of follow-up, 1490 cases (29.9%) with incident falls were identified. In the longitudinal analysis, individuals with diagnosed sarcopenia (HR: 1.32, 95% CI: 1.11-1.57) were more likely to have new-onset incident falls than their no-sarcopenia peers. Sarcopenia in the elderly is an independent risk factor for falls, with health screening and intervention reducing fall risk and improving quality of life.

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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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