Bao Y Sciscent, Marc Polanik, F Jeffrey Lorenz, Hänel W Eberly, Mark E Whitaker
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引用次数: 0
摘要
目的：利用大型患者数据库调查前庭功能障碍患者抑郁和焦虑的患病率。研究设计：回顾性队列。设置：TriNetX数据库。方法：回顾性查询TriNetX数据库，以确定患有前庭功能障碍的成年人。将前庭功能障碍患者与无前庭功能障碍患者在前庭功能障碍诊断时设定的指数事件后5年内的焦虑和抑郁率进行比较。结果：在对患有和不患有前庭疾病的患者进行分析后，在人口统计学和常见合并症的倾向评分匹配后，每个队列中确定了64153例患者。与一般人群相比，患有前庭功能障碍的患者更容易出现抑郁（相对危险度[RR] 1.37 [95% CI 1.35-1.40]）和焦虑（RR 1.51 [95% CI 1.45-1.57]）。同样，前庭疾病患者使用抗抑郁药的比例更高（RR 1.41 [95% CI 1.39-1.43]）。结论：与普通人群相比，前庭功能障碍患者抑郁和焦虑的发生率较高。
Anxiety and Depression in Patients With Vestibular Disorders.
Objective: To investigate the prevalence of depression and anxiety in patients with vestibular disorders using a large patient database.
Study design: Retrospective cohort.
Setting: The TriNetX database.
Methods: TriNetX, a deidentified database, was retrospectively queried to identify adults with vestibular disorders. The rates of anxiety and depression in patients with vestibular disorders were compared to patients without vestibular disorders within 5 years of the index event, which was set at the time of diagnosis of vestibular dysfunction.
Results: On analysis of patients with and without vestibular disorders, after propensity score matching for demographics and common comorbidities, 64,153 patients were identified in each cohort. Patients with vestibular disorders were more likely to have depression (relative risk [RR] 1.37 [95% CI 1.35-1.40]) and anxiety (RR 1.51 [95% CI 1.45-1.57]) compared to the general population. Similarly, a higher rate of antidepressant use was seen in patients with vestibular disorders (RR 1.41 [95% CI 1.39-1.43]).
Conclusion: Patients with vestibular disorders have higher rates of depression and anxiety compared to the general population.
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