Effects of Dyclonine Mucilage and Compound Lidocaine Cream as Tracheal Catheter Lubricant on Postoperative Pharyngeal Complications After General Anesthesia.

Background: The aim of this study was to observe the effects of dyclonine mucilage and compound lidocaine cream on postoperative pharyngeal complications after general anaesthesia.

Methods: Ninety patients were randomly divided into a dyclonine mucilage group (D group), a compound lidocaine cream group (L group) and a normal saline group (NS group). The primary outcomes were the incidence and severity of postoperative sore throat (POST). The secondary outcomes were postoperative cough (POC), hoarseness of voice (HOV), and the incidence of foreign body sensation (FBS) in the pharynx at 1, 6 and 24 h after surgery.

Results: The incidence of POST at 1 and 6 h after surgery in the L group was significantly lower than that in the D group (P = 0.015 and 0.012, respectively). There was no difference in the incidence of POC and HOV at 1, 6 and 24 h after surgery between the D and L groups (PPOC = 0.267, 0.236, 0.335, and PHOV = 0.500, 0.353, and 0.306, respectively). The severity scores of POST, POC and HOV were significantly lower in the L groups than in the NS group at 1and 6 h after surgery (P < 0.001, < 0.001, < 0.001, = 0.001, 0.011, and 0.005, respectively). The incidence of pharyngeal foreign body sensation in the D group was significantly greater than that in the NS group at 1 h after surgery (P = 0.012). The postoperative satisfaction scores in the L group were significantly greater than those in the D group (P = 0.007 and = 0.009).

Conclusion: Compared with dyclonine mucilage, compound lidocaine cream was associated with a lower incidence of early POST and higher postoperative satisfaction, with no increase in the incidence of pharyngeal foreign body sensation.