上呼吸道建模及下颌前移手术的验证。

IF 1 4区 医学 Q4 ENGINEERING, BIOMEDICAL
Mohd Faruq Abdul Latif, Nik Nazri Nik Ghazali, M F Abdullah, Norliza Binti Ibrahim, Roziana Mohd Razi, Tmys Tuan Ya, Irfan Anjum Badruddin, Sarfaraz Kamangar, Asa Zedan, Abdul Azeem Khan
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引用次数: 0

摘要

背景:大多数阻塞性睡眠呼吸暂停(OSA)治疗使用上气道横断面检查(UA)来确定减少间隙和UA长度。手术对所有OSA患者都是有害的,因此需要更好的评估。目的将计算流体力学(CFD)与物理模型验证相结合,提高OSA预测和湍流模型的准确性和可靠性。方法采用k-omega海温湍流模型对OSA进行CFD分析。利用SLS建立UA的物理模型进行CFD仿真。然后将UA的物理模型与osa推荐的CFD湍流模型进行比较,以验证模拟与物理现实的一致性。结果下颌骨前移手术后平均UA压差明显降低。术后湍流动能(TKE)增加,表明湍流增加。物理模型的交叉验证证实了OSA CFD湍流模拟的有效性。结论UA模拟与物理模型匹配可改善OSA评估。建立物理模型的CFD是评估OSA治疗,尤其是外科手术的可靠方法。术后TKE的增加需要更多的研究来确定其对OSA治疗结果的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Upper airways modelling and validation of mandibular advancement surgery.

Background: Most Obstructive Sleep Apnoea (OSA) treatments use cross-sectional examination of the Upper Airways (UA) to determine decreasing gap and UA length. Surgery is detrimental to all OSA patients, stressing the need for better assessment.ObjectiveThis study integrates Computational Fluid Dynamics (CFD) with physical model validation to improve OSA prediction and turbulence model accuracy and dependability.MethodsThe k-omega SST turbulence model is used to analyse OSA using CFD. SLS is used to build a physical model of the UA for CFD simulations. The UA's physical model is then compared to the OSA-recommended CFD turbulence model to verify simulation-physical reality coherence.ResultThe average UA pressure differential decreases considerably after mandibular advancement surgery. The Turbulent Kinetic Energy (TKE) increases after surgery, indicating more turbulence. Cross-validation of the physical model confirms the OSA CFD turbulence simulation's validity.ConclusionThe study concludes that matching UA simulations with physical models improves OSA assessments. CFD with established physical models is a reliable method for assessing OSA therapy, especially surgical operations. The post-surgery increase in TKE needs more study to determine its effects on OSA treatment outcomes.

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来源期刊
Bio-medical materials and engineering
Bio-medical materials and engineering 工程技术-材料科学:生物材料
CiteScore
1.80
自引率
0.00%
发文量
73
审稿时长
6 months
期刊介绍: The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.
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