Alvi H. Islam, Claudia Alvizuri, Hailemichael Desalegn, Emily Stephenson, Francisco Idalsoaga, Luis Antonio Diaz, John K. MacDonald, Gene Y. Im, Ashwani K. Singal, Vipul Jairath, Mohammad Qasim Khan, Juan Pablo Arab
{"title":"治疗重度酒精相关性肝炎的药理学策略:一项系统综述和荟萃分析","authors":"Alvi H. Islam, Claudia Alvizuri, Hailemichael Desalegn, Emily Stephenson, Francisco Idalsoaga, Luis Antonio Diaz, John K. MacDonald, Gene Y. Im, Ashwani K. Singal, Vipul Jairath, Mohammad Qasim Khan, Juan Pablo Arab","doi":"10.1016/j.cgh.2025.05.016","DOIUrl":null,"url":null,"abstract":"Alcohol-associated hepatitis (AH) is a severe form of alcohol-associated liver disease, with a short-term mortality of up to 50% within three months. The aim of this systematic review was to determine the optimal pharmacological treatment for severe AH that results in better survival outcomes.","PeriodicalId":10347,"journal":{"name":"Clinical Gastroenterology and Hepatology","volume":"12 1","pages":""},"PeriodicalIF":12.0000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pharmacological Strategies for the Management of Severe Alcohol-associated Hepatitis: A Systematic Review and Meta-analysis\",\"authors\":\"Alvi H. Islam, Claudia Alvizuri, Hailemichael Desalegn, Emily Stephenson, Francisco Idalsoaga, Luis Antonio Diaz, John K. MacDonald, Gene Y. Im, Ashwani K. Singal, Vipul Jairath, Mohammad Qasim Khan, Juan Pablo Arab\",\"doi\":\"10.1016/j.cgh.2025.05.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Alcohol-associated hepatitis (AH) is a severe form of alcohol-associated liver disease, with a short-term mortality of up to 50% within three months. The aim of this systematic review was to determine the optimal pharmacological treatment for severe AH that results in better survival outcomes.\",\"PeriodicalId\":10347,\"journal\":{\"name\":\"Clinical Gastroenterology and Hepatology\",\"volume\":\"12 1\",\"pages\":\"\"},\"PeriodicalIF\":12.0000,\"publicationDate\":\"2025-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Gastroenterology and Hepatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cgh.2025.05.016\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Gastroenterology and Hepatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.cgh.2025.05.016","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Pharmacological Strategies for the Management of Severe Alcohol-associated Hepatitis: A Systematic Review and Meta-analysis
Alcohol-associated hepatitis (AH) is a severe form of alcohol-associated liver disease, with a short-term mortality of up to 50% within three months. The aim of this systematic review was to determine the optimal pharmacological treatment for severe AH that results in better survival outcomes.
期刊介绍:
Clinical Gastroenterology and Hepatology (CGH) is dedicated to offering readers a comprehensive exploration of themes in clinical gastroenterology and hepatology. Encompassing diagnostic, endoscopic, interventional, and therapeutic advances, the journal covers areas such as cancer, inflammatory diseases, functional gastrointestinal disorders, nutrition, absorption, and secretion.
As a peer-reviewed publication, CGH features original articles and scholarly reviews, ensuring immediate relevance to the practice of gastroenterology and hepatology. Beyond peer-reviewed content, the journal includes invited key reviews and articles on endoscopy/practice-based technology, health-care policy, and practice management. Multimedia elements, including images, video abstracts, and podcasts, enhance the reader's experience. CGH remains actively engaged with its audience through updates and commentary shared via platforms such as Facebook and Twitter.