“F-53B通过抑制V-ATPase-AMPK轴在神经细胞中破坏能量代谢”的更正[j] Hazard Mater。(487 (2025) 137111)

IF 11.3 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL
Yue Zhang, Tingting Li, Xueman Ding, Li Liu, Runjiang Ma, Wenqi Qin, Chulin Yan, Chun Wang, Jingjing Zhang, Mulatibieke Keerman, Qiang Niu
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And we mistakenly wrote the annotation <sup>***</sup><em>P</em> &lt; 0.001 as <sup>***</sup><em>P</em> &lt; 0.005 for the figures in the article.<figure><span><img alt=\"Fig. 4\" aria-describedby=\"cap0005\" height=\"998\" src=\"https://ars.els-cdn.com/content/image/1-s2.0-S0304389425018072-gr1.jpg\"/><ol><li><span><span>Download: <span>Download high-res image (673KB)</span></span></span></li><li><span><span>Download: <span>Download full-size image</span></span></span></li></ol></span><span><span><p><span>Fig. 4</span>. F-53B exposure inhibits TRPML1 expression and reduces lysosomal Ca<sup>2 +</sup> release in neuronal cells. (A-C) Western blot and relative quantification of TRPML1 and CaMKK2 in C8-D1A and SH-SY5Y cells. (D) Fluorescence assay and quantitative fluorescence analysis images of lysosomal Ca<sup>2+</sup> in C8-D1A cells. (E) Fluorescence assay and quantitative fluorescence analysis images of lysosomal Ca<sup>2+</sup> in SH-SY5Y cells. 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引用次数: 0

摘要

对于上述已发表版本中Fig. 4和Fig. 8存在错误,特别是在第8页无意中使用了Fig. 4E中2.5 μM F-53B组的Lyso Tracker图像。在第13页,图8B中的RSV+F-53B组无意中重复使用了MitoSOx-red和Merge图像。我们错误地写了注释***P <;0.001为***P <;文章中的数字为0.005。下载:下载高分辨率图片(673KB)下载:下载全尺寸图片4. F-53B暴露抑制TRPML1表达并减少神经元细胞中溶酶体Ca2 +释放。(A-C) C8-D1A和SH-SY5Y细胞中TRPML1和CaMKK2的Western blot和相对定量。(D) C8-D1A细胞中溶酶体Ca2+的荧光测定和定量荧光分析图像。(E) SH-SY5Y细胞中溶酶体Ca2+的荧光测定和定量荧光分析图像。数值为平均值±SD (n = 3个重复)。* * * p & lt; 0.05, p & lt; 0.01 * * * p & lt; 0.001与对照组相比。下载:下载高分辨率图片(914KB)下载:下载全尺寸图片8. RSV减轻F-53B诱导的线粒体损伤,恢复神经元细胞ATP水平。(A) RSV干预后C8-D1A细胞mtROS的代表性图像。(B) RSV干预后SH-SY5Y细胞mtROS的代表性图像。(C) a和b的定量分析(D) E的定量分析(E) RSV干预后C8-D1A和SH-SY5Y细胞MMP的代表性图像。红色信号为JC-1聚合体,绿色信号为JC-1单体,CCCP为阳性对照。(F) RSV干预后C8-D1A细胞ATP水平图。(G) RSV干预后SH-SY5Y细胞ATP水平图。数值为平均值±SD (n = 3个重复)。* * * p & lt; 0.05, p & lt; 0.01 * * * p & lt; 0.001与对照组相比。&p < 0.05, &;&p < 0.01, &;,&p <; 0.001与F-53B组相比。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Corrigendum to “F-53B disrupts energy metabolism by inhibiting the V-ATPase-AMPK axis in neuronal cells,” [ J. Hazard Mater. (487 (2025) 137111]
The authors regret that there were errors in Fig. 4 and Fig. 8 in the published version mentioned above, specifically, on page 8, an incorrect Lyso Tracker image of 2.5 μM F-53B group in Fig. 4E was inadvertently used. On page 13, the MitoSOx-red and Merge images were unintentionally reused in the RSV+F-53B group in Fig. 8B. And we mistakenly wrote the annotation ***P < 0.001 as ***P < 0.005 for the figures in the article.
Fig. 4
  1. Download: Download high-res image (673KB)
  2. Download: Download full-size image

Fig. 4. F-53B exposure inhibits TRPML1 expression and reduces lysosomal Ca2 + release in neuronal cells. (A-C) Western blot and relative quantification of TRPML1 and CaMKK2 in C8-D1A and SH-SY5Y cells. (D) Fluorescence assay and quantitative fluorescence analysis images of lysosomal Ca2+ in C8-D1A cells. (E) Fluorescence assay and quantitative fluorescence analysis images of lysosomal Ca2+ in SH-SY5Y cells. Values represent the mean ± SD (n = 3 replicates). *p < 0.05, **p < 0.01, ***p < 0.001 compared with the control group.

Fig. 8
  1. Download: Download high-res image (914KB)
  2. Download: Download full-size image

Fig. 8. RSV relieves mitochondrial damage induced by F-53B and restores cellular ATP levels in neuronal cells. (A) Representative images of mtROS in C8-D1A cells after intervention with RSV. (B) Representative images of mtROS in SH-SY5Y cells after intervention with RSV. (C) Quantitative analyses of a and B. (D) Quantitative analyses of E. (E) Representative images of MMP in C8-D1A and SH-SY5Y cells after intervention with RSV. Red signals indicate JC-1 aggregate, Green signals indicate JC-1 monomer, and CCCP is used as a positive control. (F) Plot of ATP levels in C8-D1A cells after intervention with RSV. (G) Plot of ATP levels in SH-SY5Y cells after intervention with RSV. Values represent the mean ± SD (n = 3 replicates). *p < 0.05, **p < 0.01, ***p < 0.001 compared with the control group. &p < 0.05, & &p < 0.01, & & &p < 0.001 compared with the F-53B group.

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来源期刊
Journal of Hazardous Materials
Journal of Hazardous Materials 工程技术-工程:环境
CiteScore
25.40
自引率
5.90%
发文量
3059
审稿时长
58 days
期刊介绍: The Journal of Hazardous Materials serves as a global platform for promoting cutting-edge research in the field of Environmental Science and Engineering. Our publication features a wide range of articles, including full-length research papers, review articles, and perspectives, with the aim of enhancing our understanding of the dangers and risks associated with various materials concerning public health and the environment. It is important to note that the term "environmental contaminants" refers specifically to substances that pose hazardous effects through contamination, while excluding those that do not have such impacts on the environment or human health. Moreover, we emphasize the distinction between wastes and hazardous materials in order to provide further clarity on the scope of the journal. We have a keen interest in exploring specific compounds and microbial agents that have adverse effects on the environment.
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