肺腺癌小肠转移一例报告及文献复习。

IF 1.7 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Rui-Xian Shi, Zhen-Ping Guo, Xin Li, Hui Wang, Bo Wang, Ming-Yue Du, Ji-Jun Wang, Zhen-Yu Dong
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引用次数: 0

摘要

背景:肺癌在胃肠道的临床转移率极低。患有肺癌小肠转移的个体通常比身体其他部位转移的患者预后较差,生存期较短。因此,对肺癌胃肠道转移患者进行早期诊断和制定系统的治疗方案具有重要意义。病例总结:本病例为59岁女性患者,诊断为肺腺癌,因小肠转移而发生肠梗阻。腺癌诊断后影像学证实转移至小肠,最终导致晚期肠梗阻。保守治疗无效,后期发展为肠穿孔。从而导致腹膜炎和感染性中毒性休克等严重的临床表现。积极的手术切除减轻了疾病进展甚至死亡的风险,极大地改善了患者的预后并延长了她的生存期。结论:出现急性腹部症状的肺癌患者应注意小肠转移的可能性。肠穿孔通常发生在疾病的晚期。此外,积极的手术治疗可以降低各种并发症的风险,如腹膜炎,感染性中毒性休克,甚至死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Small intestine metastasis from lung adenocarcinoma: A case report and review of literature.

Background: The clinical metastasis rate of lung cancer is tremendously low in gastrointestinal tract. Individuals enduring small intestine metastasis of lung cancer are normally featured by less desirable prognosis and shorter survival than those with metastasis in other parts of the body. As a consequence, it holds crucial significance to conduct early diagnosis and development of systematic treatment for patients with gastrointestinal metastasis in lung cancer.

Case summary: In this case, a 59-year-old female patient, diagnosed with lung adenocarcinoma, experienced intestinal obstruction attributable to subsequent small intestinal metastasis. Imaging confirmed the metastasis to the small intestine after the adenocarcinoma diagnosis, ultimately giving rise to advanced-stage intestinal obstruction. Conservative treatment proved ineffective, progressing to intestinal perforation in the later stages. This resulted in peritonitis and infectious toxic shock and other serious clinical manifestations. Aggressive surgical resection mitigated the risk of disease progression and even fatality, which tremendously ameliorated the patient's prognosis and prolonged her survival.

Conclusion: Patients enduring lung cancer who exhibit acute abdominal symptoms should be mindful of the potential for small intestinal metastasis. Intestinal perforation typically occurs in advanced stages of the disease. Moreover, and aggressive surgical treatment can mitigate the risk of multifarious complications such as peritonitis, infectious toxic shock, and even fatality.

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