Saitiel Sandoval Gonzalez, Weilin Song, Joseph K Privratsky, Jack Lemon, Edmund Tsui
{"title":"血管化梅毒性虹膜病变的扫描源前段光学相干断层扫描。","authors":"Saitiel Sandoval Gonzalez, Weilin Song, Joseph K Privratsky, Jack Lemon, Edmund Tsui","doi":"10.1080/09273948.2025.2514693","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe the appearance and resolution of a vascularized iris nodule in a case of ocular syphilis with swept-source anterior segment optical coherence tomography (SS AS-OCT) imaging.</p><p><strong>Methods: </strong>Case report.</p><p><strong>Results: </strong>A 73-year-old male with a history of ocular syphilis presented with anterior uveitis of the left eye characterized by mutton fat keratic precipitates, anterior chamber cells, hypopyon mixed with hemorrhage, and a vascularized iris nodule. SS AS-OCT similarly showed keratic precipitates, anterior chamber cells, and an iris lesion with anterior hyperreflectivity and shadowing. Systemic workup revealed a new syphilis infection with rapid plasma reagin (RPR) titer of 1:512. After completing a 14-day course of intravenous penicillin and topical steroid treatment, there was resolution of these ocular findings.</p><p><strong>Conclusion: </strong>Ocular syphilis should be considered on the differential diagnosis for vascularized iris lesions. Our case demonstrates SS-AS-OCT findings in this rare presentation of ocular syphilis.</p>","PeriodicalId":19406,"journal":{"name":"Ocular Immunology and Inflammation","volume":" ","pages":"1-3"},"PeriodicalIF":2.6000,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Swept-Source Anterior Segment Optical Coherence Tomography of a Vascularized Syphilitic Iris Lesion.\",\"authors\":\"Saitiel Sandoval Gonzalez, Weilin Song, Joseph K Privratsky, Jack Lemon, Edmund Tsui\",\"doi\":\"10.1080/09273948.2025.2514693\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To describe the appearance and resolution of a vascularized iris nodule in a case of ocular syphilis with swept-source anterior segment optical coherence tomography (SS AS-OCT) imaging.</p><p><strong>Methods: </strong>Case report.</p><p><strong>Results: </strong>A 73-year-old male with a history of ocular syphilis presented with anterior uveitis of the left eye characterized by mutton fat keratic precipitates, anterior chamber cells, hypopyon mixed with hemorrhage, and a vascularized iris nodule. SS AS-OCT similarly showed keratic precipitates, anterior chamber cells, and an iris lesion with anterior hyperreflectivity and shadowing. Systemic workup revealed a new syphilis infection with rapid plasma reagin (RPR) titer of 1:512. After completing a 14-day course of intravenous penicillin and topical steroid treatment, there was resolution of these ocular findings.</p><p><strong>Conclusion: </strong>Ocular syphilis should be considered on the differential diagnosis for vascularized iris lesions. Our case demonstrates SS-AS-OCT findings in this rare presentation of ocular syphilis.</p>\",\"PeriodicalId\":19406,\"journal\":{\"name\":\"Ocular Immunology and Inflammation\",\"volume\":\" \",\"pages\":\"1-3\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ocular Immunology and Inflammation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09273948.2025.2514693\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ocular Immunology and Inflammation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09273948.2025.2514693","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Swept-Source Anterior Segment Optical Coherence Tomography of a Vascularized Syphilitic Iris Lesion.
Purpose: To describe the appearance and resolution of a vascularized iris nodule in a case of ocular syphilis with swept-source anterior segment optical coherence tomography (SS AS-OCT) imaging.
Methods: Case report.
Results: A 73-year-old male with a history of ocular syphilis presented with anterior uveitis of the left eye characterized by mutton fat keratic precipitates, anterior chamber cells, hypopyon mixed with hemorrhage, and a vascularized iris nodule. SS AS-OCT similarly showed keratic precipitates, anterior chamber cells, and an iris lesion with anterior hyperreflectivity and shadowing. Systemic workup revealed a new syphilis infection with rapid plasma reagin (RPR) titer of 1:512. After completing a 14-day course of intravenous penicillin and topical steroid treatment, there was resolution of these ocular findings.
Conclusion: Ocular syphilis should be considered on the differential diagnosis for vascularized iris lesions. Our case demonstrates SS-AS-OCT findings in this rare presentation of ocular syphilis.
期刊介绍：
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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