Konstantin Warneke, Julia Meder, Gerit Plöschberger, Manuel Oraže, Maximilian Zechner, Daniel Jochum, Stanislav D Siegel, Andreas Konrad
{"title":"测量误差能否解释肌肉和肌腱僵硬度与活动范围之间关系的差异？-盲法可靠性和客观性研究。","authors":"Konstantin Warneke, Julia Meder, Gerit Plöschberger, Manuel Oraže, Maximilian Zechner, Daniel Jochum, Stanislav D Siegel, Andreas Konrad","doi":"10.1007/s00421-025-05814-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The relationship between range of motion (ROM) and underlying parameters such as stiffness (ST) remains controversial throughout the literature. Therefore, this study aimed to analyze the potential role of accumulated measurement errors and subjective influences through a comprehensive assessment of both systematic and random errors on the correlation between tissue ST and ROM.</p><p><strong>Methods: </strong>A total of 75 subjects participated in this double-blinded reliability evaluation. Besides muscle thickness assessments, lower legs' ST in the calf muscle and Achilles tendon (shear-wave elastography [SWE] and viscoelastic parameters [MyotonPRO], respectively) were correlated with ankle dorsiflexion ROM (knee-to-wall test [KtW]).</p><p><strong>Results: </strong>Ultrasound image acquisition (i.e., muscle thickness and ST) and myotonometry showed intrasession reliability (ICC = 0.93-0.99 and 0.72-0.99, respectively) depending on the device. Only for MyotonPRO, there were meaningful systematic and random errors only for decrement (SEM = 0.002-10.629; MAE = 0.01-24.84). ROM showed ICC > 0.99, while for all parameters interday reliability declined (ICC = 0.395-0.88). Interrater objectivity showed ICC = 0.61-0.91 for ultrasound analysis and 0.66-0.96 for myotonometry. No agreement (ICC = 0-0.09) between different ST measurements was observed, while relationship between ST and ROM depended on the investigator (r = 0.21-0.26 versus r = - 0.02--0.07).</p><p><strong>Discussion: </strong>While aligned with reliability and objectivity metrics from the literature, our results demonstrate that ST determination is device-dependent, and its relationship with ROM varies by measurement day and investigator. This underlines clinically relevant measurement errors in ST evaluation, calling for advance standardization to improve reliability and objectivity, while measurement errors quantified beyond the ICC must not be neglected in future studies.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Can measurement errors explain variance in the relationship between muscle- and tendon stiffness and range of motion?-a blinded reliability and objectivity study.\",\"authors\":\"Konstantin Warneke, Julia Meder, Gerit Plöschberger, Manuel Oraže, Maximilian Zechner, Daniel Jochum, Stanislav D Siegel, Andreas Konrad\",\"doi\":\"10.1007/s00421-025-05814-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The relationship between range of motion (ROM) and underlying parameters such as stiffness (ST) remains controversial throughout the literature. Therefore, this study aimed to analyze the potential role of accumulated measurement errors and subjective influences through a comprehensive assessment of both systematic and random errors on the correlation between tissue ST and ROM.</p><p><strong>Methods: </strong>A total of 75 subjects participated in this double-blinded reliability evaluation. Besides muscle thickness assessments, lower legs' ST in the calf muscle and Achilles tendon (shear-wave elastography [SWE] and viscoelastic parameters [MyotonPRO], respectively) were correlated with ankle dorsiflexion ROM (knee-to-wall test [KtW]).</p><p><strong>Results: </strong>Ultrasound image acquisition (i.e., muscle thickness and ST) and myotonometry showed intrasession reliability (ICC = 0.93-0.99 and 0.72-0.99, respectively) depending on the device. Only for MyotonPRO, there were meaningful systematic and random errors only for decrement (SEM = 0.002-10.629; MAE = 0.01-24.84). ROM showed ICC > 0.99, while for all parameters interday reliability declined (ICC = 0.395-0.88). Interrater objectivity showed ICC = 0.61-0.91 for ultrasound analysis and 0.66-0.96 for myotonometry. No agreement (ICC = 0-0.09) between different ST measurements was observed, while relationship between ST and ROM depended on the investigator (r = 0.21-0.26 versus r = - 0.02--0.07).</p><p><strong>Discussion: </strong>While aligned with reliability and objectivity metrics from the literature, our results demonstrate that ST determination is device-dependent, and its relationship with ROM varies by measurement day and investigator. This underlines clinically relevant measurement errors in ST evaluation, calling for advance standardization to improve reliability and objectivity, while measurement errors quantified beyond the ICC must not be neglected in future studies.</p>\",\"PeriodicalId\":12005,\"journal\":{\"name\":\"European Journal of Applied Physiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-06-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Applied Physiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00421-025-05814-1\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Applied Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00421-025-05814-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
Can measurement errors explain variance in the relationship between muscle- and tendon stiffness and range of motion?-a blinded reliability and objectivity study.
Introduction: The relationship between range of motion (ROM) and underlying parameters such as stiffness (ST) remains controversial throughout the literature. Therefore, this study aimed to analyze the potential role of accumulated measurement errors and subjective influences through a comprehensive assessment of both systematic and random errors on the correlation between tissue ST and ROM.
Methods: A total of 75 subjects participated in this double-blinded reliability evaluation. Besides muscle thickness assessments, lower legs' ST in the calf muscle and Achilles tendon (shear-wave elastography [SWE] and viscoelastic parameters [MyotonPRO], respectively) were correlated with ankle dorsiflexion ROM (knee-to-wall test [KtW]).
Results: Ultrasound image acquisition (i.e., muscle thickness and ST) and myotonometry showed intrasession reliability (ICC = 0.93-0.99 and 0.72-0.99, respectively) depending on the device. Only for MyotonPRO, there were meaningful systematic and random errors only for decrement (SEM = 0.002-10.629; MAE = 0.01-24.84). ROM showed ICC > 0.99, while for all parameters interday reliability declined (ICC = 0.395-0.88). Interrater objectivity showed ICC = 0.61-0.91 for ultrasound analysis and 0.66-0.96 for myotonometry. No agreement (ICC = 0-0.09) between different ST measurements was observed, while relationship between ST and ROM depended on the investigator (r = 0.21-0.26 versus r = - 0.02--0.07).
Discussion: While aligned with reliability and objectivity metrics from the literature, our results demonstrate that ST determination is device-dependent, and its relationship with ROM varies by measurement day and investigator. This underlines clinically relevant measurement errors in ST evaluation, calling for advance standardization to improve reliability and objectivity, while measurement errors quantified beyond the ICC must not be neglected in future studies.
期刊介绍：
The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.
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