Yang You, Mengrui Liu, Na Yan, Dashuai Zhu, Xiao Cheng, Yilan Hu, Yuan Li, Zhen Qin, Zhixin Zhu, Ke Cheng
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Smart Materials and Devices for Enhanced Delivery of Extracellular Vesicles
Extracellular vesicles (EVs) are vesicle-like structures secreted by various cell types, playing a crucial role in cell communication. As an efficient and safe therapeutic carrier, EVs offer new insights and methods for disease treatment and drug development due to high stability, low immunogenicity, and broad resources. However, current applications on EV-based delivery systems are still challenging, and additional strategies are needed to achieve precise and targeted delivery, enhance stability and safety, and avoid unnecessary immune reactions or side effects. This review summarizes the latest progress in using smart materials or devices to enhance EV delivery, aiming to provide a reference for designing novel and efficient EV-based targeted delivery strategies.
期刊介绍：
Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.
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