中药单一成分对宫颈癌体外模型药理作用的最新进展

Min Zhao , Liuxiang Feng , Wenhua Li
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引用次数: 0

摘要

目的对迄今为止有关中药单体治疗宫颈癌的文献进行综述,重点探讨其作用机制及在宫颈癌防治中的应用前景。方法计算机检索PubMed、Medline、CNKI等数据库至今的相关文献。搜索关键词为“宫颈癌、中药单体及机制”。选择与本文相匹配的文献进行整理、总结、总结。结果与结论CC的发育和转移是一个涉及多种信号通路的复杂过程。尽管在CC治疗方面取得了重大进展,但仍存在一些不良反应,包括感染、骨髓抑制和血液毒性。因此,迫切需要开发新的、有效的、安全的、负担得起的抗CC药物。中药单体因其提取方便、安全、低毒、副作用小等优点,在抗CC研究领域受到越来越多的关注。中药单体通过多种机制作用于多个靶点,不仅可以抑制CC细胞的生长、增殖、侵袭、迁移,还可以促进CC细胞的凋亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The latest progress on the pharmacological effects of single components of traditional Chinese medicine in in vitro models of cervical cancer

Objective

This article attempts to comprehensively review all literature on traditional Chinese medicine monomers for the treatment of cervical cancer(CC) to date, with a focus on exploring their mechanisms of action and future prospects in the prevention and treatment of cervical cancer.

Method

A computer was used to search for relevant literature from databases such as PubMed, Medline, and CNKI up to now. The search keywords were "cervical cancer, traditional Chinese medicine monomers (TCM) and mechanisms". Literature that matched this article was selected for sorting, summarizing, and summarizing.

Result and conclusion

The development and transfer of CC is a complex process involving many signaling pathways. Although significant progress has been made in the treatment of CC, there are still some adverse reactions, including infection, bone marrow suppression, and hematotoxicity. Therefore, there is an urgent need to develop new, effective, safe, and affordable anti CC drugs. Traditional Chinese medicine monomers have attracted increasing attention in the field of anti CC research due to their advantages such as easy extraction, safety, low toxicity, and minimal side effects. Traditional Chinese medicine monomers act on multiple targets through various mechanisms, not only inhibiting the growth, proliferation, invasion, and migration of CC cells, but also promoting their apoptosis.
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