{"title":"经阴道手术后阴道菌血症:辅助生殖技术中一种罕见的并发症","authors":"Naoki Okawa , Mutsuka Kurihara , Rika Kurata , Emiri Muranaka , Yuji Nishihara , Kosuke Ito , Yasunobu Endo , Ryota Hase","doi":"10.1016/j.diagmicrobio.2025.116947","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div><em>Fannyhessea vaginae</em> is commonly found in vaginal flora and associated with bacterial vaginosis, but rarely causes invasive infections. Few cases of <em>F. vaginae</em> bacteremia have been reported, primarily in the context of pregnancy or gynecological procedures.</div></div><div><h3>Case</h3><div>A 40-year-old woman presented with fever and right lower abdominal pain two weeks after undergoing transvaginal procedures for assisted reproductive technology. She had no symptoms of bacterial vaginosis. Magnetic resonance imaging revealed a 9 cm tubo-ovarian mass. Blood cultures and surgical specimens grew gram-positive cocci, later identified as <em>F. vaginae</em>. The patient recovered following right salpingo-oophorectomy and seven days of cefmetazole therapy.</div></div><div><h3>Conclusion</h3><div>This case demonstrates that <em>F. vaginae</em> can cause serious infections following transvaginal procedures, even in the absence of symptoms of bacterial vaginosis. Clinicians should consider <em>F. vaginae</em> as a potential pathogen in post-gynecological procedure infections, particularly when anaerobic blood cultures become positive.</div></div>","PeriodicalId":11329,"journal":{"name":"Diagnostic microbiology and infectious disease","volume":"113 2","pages":"Article 116947"},"PeriodicalIF":2.1000,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fannyhessea vaginae bacteremia following transvaginal procedures: A rare complication in assisted reproductive technology\",\"authors\":\"Naoki Okawa , Mutsuka Kurihara , Rika Kurata , Emiri Muranaka , Yuji Nishihara , Kosuke Ito , Yasunobu Endo , Ryota Hase\",\"doi\":\"10.1016/j.diagmicrobio.2025.116947\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div><em>Fannyhessea vaginae</em> is commonly found in vaginal flora and associated with bacterial vaginosis, but rarely causes invasive infections. Few cases of <em>F. vaginae</em> bacteremia have been reported, primarily in the context of pregnancy or gynecological procedures.</div></div><div><h3>Case</h3><div>A 40-year-old woman presented with fever and right lower abdominal pain two weeks after undergoing transvaginal procedures for assisted reproductive technology. She had no symptoms of bacterial vaginosis. Magnetic resonance imaging revealed a 9 cm tubo-ovarian mass. Blood cultures and surgical specimens grew gram-positive cocci, later identified as <em>F. vaginae</em>. The patient recovered following right salpingo-oophorectomy and seven days of cefmetazole therapy.</div></div><div><h3>Conclusion</h3><div>This case demonstrates that <em>F. vaginae</em> can cause serious infections following transvaginal procedures, even in the absence of symptoms of bacterial vaginosis. Clinicians should consider <em>F. vaginae</em> as a potential pathogen in post-gynecological procedure infections, particularly when anaerobic blood cultures become positive.</div></div>\",\"PeriodicalId\":11329,\"journal\":{\"name\":\"Diagnostic microbiology and infectious disease\",\"volume\":\"113 2\",\"pages\":\"Article 116947\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic microbiology and infectious disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0732889325002706\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic microbiology and infectious disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0732889325002706","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Fannyhessea vaginae bacteremia following transvaginal procedures: A rare complication in assisted reproductive technology
Background
Fannyhessea vaginae is commonly found in vaginal flora and associated with bacterial vaginosis, but rarely causes invasive infections. Few cases of F. vaginae bacteremia have been reported, primarily in the context of pregnancy or gynecological procedures.
Case
A 40-year-old woman presented with fever and right lower abdominal pain two weeks after undergoing transvaginal procedures for assisted reproductive technology. She had no symptoms of bacterial vaginosis. Magnetic resonance imaging revealed a 9 cm tubo-ovarian mass. Blood cultures and surgical specimens grew gram-positive cocci, later identified as F. vaginae. The patient recovered following right salpingo-oophorectomy and seven days of cefmetazole therapy.
Conclusion
This case demonstrates that F. vaginae can cause serious infections following transvaginal procedures, even in the absence of symptoms of bacterial vaginosis. Clinicians should consider F. vaginae as a potential pathogen in post-gynecological procedure infections, particularly when anaerobic blood cultures become positive.
期刊介绍:
Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.