基于PocketNet的头颈部肿瘤体积自动分割。

Awj Twam, Adrian Celaya, Evan Lim, Khaled Elsayes, David Fuentes, Tucker Netherton
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摘要

头颈癌(HNC)是一个重大的全球健康负担,通常需要复杂的治疗策略,包括手术、化疗和放疗。准确描绘肿瘤体积对于有效治疗至关重要,特别是在磁共振引导的干预中,软组织造影剂增强了肿瘤边界的可视化。人工分割总肿瘤体积(GTV)是一项劳动密集、耗时且易发生变化的工作,这促使了自动分割技术的发展。卷积神经网络(cnn)已经成为这项任务的强大工具,在速度和一致性方面提供了显著的改进。在这项研究中,我们作为Team Pocket参与了HNTS-MRG 2024 Grand Challenge的任务1,该任务的重点是HNC放疗前MR图像中原发肿瘤(GTVp)和淋巴结肿瘤(GTVn)的总肿瘤体积分割。我们对轻量级CNN架构PocketNet的应用进行了评估。挑战的最后测试阶段的结果表明,PocketNet实现了GTVn的聚合Dice Sorensen系数(DSCagg)为0.808,GTVp为0.732,总体平均性能为0.77。这些发现证明了PocketNet作为一种高效、准确的解决方案的潜力,可以在磁共振引导的HNC治疗工作流程中自动分割肿瘤,并有机会进一步优化以提高性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Head and Neck Gross Tumor Volume Automatic Segmentation Using PocketNet.

Head and neck cancer (HNC) represents a significant global health burden, often requiring complex treatment strategies, including surgery, chemotherapy, and radiation therapy. Accurate delineation of tumor volumes is critical for effective treatment, particularly in MR-guided interventions, where soft tissue contrast enhances visualization of tumor boundaries. Manual segmentation of gross tumor volumes (GTV) is labor intensive, time-consuming and prone to variability, motivating the development of automated segmentation techniques. Convolutional neural networks (CNNs) have emerged as powerful tools in this task, offering significant improvements in speed and consistency. In this study, we participated as Team Pocket in Task 1 of the HNTS-MRG 2024 Grand Challenge, which focuses on the segmentation of gross tumor volumes of the primary tumor (GTVp) and the nodal tumor (GTVn) in pre-radiotherapy MR images for HNC. We evaluated the application of PocketNet, a lightweight CNN architecture, for this task. Results for the final test phase of the challenge show that PocketNet achieved an aggregated Dice Sorensen Coefficient (DSCagg) of 0.808 for GTVn and 0.732 for GTVp, with an overall mean performance of 0.77. These findings demonstrate the potential of PocketNet as an efficient and accurate solution for automated tumor segmentation in MR-guided HNC treatment workflows, with opportunities for further optimization to enhance performance.

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