Investigation of factors influencing anxiety and depression symptoms after therapy in 200 patients diagnosed with primary liver cancer.

Background: Patients undergoing interventional therapy for liver cancer experience severe psychological pain and are prone to anxiety and depression.

Aim: To explore factors influencing anxiety and depression symptoms in 200 patients diagnosed with primary liver cancer.

Methods: Data from 200 individuals diagnosed with primary liver cancer and admitted to the authors' hospital (January 2022 to January 2024) were divided into 2 groups according to psychological status: Normal (n = 100); and anxiety and depression (n = 100). Through a questionnaire survey of patients and their families, single and multifactor factors of anxiety and depression in the postoperative interventional treatment of patients with primary liver cancer were analyzed.

Results: Univariate analysis revealed no statistical differences between the 2 groups in terms of chronic disease, sex, liver function, Child grade, and age (P > 0.05). However, there were statistical differences in payment method, disease cognition, number of interventional treatments, per capita income, and educational level (P < 0.05). Multivariate logistic regression analysis revealed that educational level, per capita income, disease cognition, payment method, and number of interventional treatments were all independent factors influencing postoperative anxiety and depression symptoms after interventional therapy in patients diagnosed with primary liver cancer, and the comparisons were statistically significant (P < 0.05).

Conclusion: Analysis of associated risk factors can strengthen the clinical screening of patients with liver cancer at high risk for postoperative anxiety and depression symptoms and improve their prognosis.