Wei Jiang, Yu-Zhi Qiu, Hu-Tao Xi, Hui-Hui Ma, Xin Wu, Xiao-Mei Yuan, Wen-Yan Wang, Hong Kong, Xiao-Ping Li
{"title":"原发性甲状旁腺功能亢进所致可逆性扩张型心肌病1例。","authors":"Wei Jiang, Yu-Zhi Qiu, Hu-Tao Xi, Hui-Hui Ma, Xin Wu, Xiao-Mei Yuan, Wen-Yan Wang, Hong Kong, Xiao-Ping Li","doi":"10.4330/wjc.v17.i5.105670","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Dilated cardiomyopathy (DCM) is a common cause of systolic heart failure, and is the most prevalent type of non-ischemic cardiomyopathy. Primary hyperparathyroidism (PHPT) is characterized by hypercalcemia and excessive secretion of parathyroid hormone (PTH). Generally, PHPT is asymptomatic and is incidentally identified during routine laboratory assessments.</p><p><strong>Case summary: </strong>This case report details a 52-year-old man diagnosed with DCM and refractory hypercalcemia, who presented with clinical manifestations including dyspnea, recurrent anorexia, and abdominal distention. Laboratory investigations indicated an elevated serum PTH level, and the sestamibi scan suggested the presence of a parathyroid adenoma. Hence, the patient underwent a parathyroidectomy, which pathologically confirmed the diagnosis of a parathyroid adenoma. Postoperatively, the patient's hypercalcemia was corrected, the dimensions of the cardiac chambers were reduced, and there was a marked improvement in cardiac function.</p><p><strong>Conclusion: </strong>Our findings emphasize the importance of PTH assessment in patients with DCM and concurrent hypercalcemia.</p>","PeriodicalId":23800,"journal":{"name":"World Journal of Cardiology","volume":"17 5","pages":"105670"},"PeriodicalIF":2.8000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146955/pdf/","citationCount":"0","resultStr":"{\"title\":\"Reversible dilated cardiomyopathy caused by primary hyperparathyroidism: A case report.\",\"authors\":\"Wei Jiang, Yu-Zhi Qiu, Hu-Tao Xi, Hui-Hui Ma, Xin Wu, Xiao-Mei Yuan, Wen-Yan Wang, Hong Kong, Xiao-Ping Li\",\"doi\":\"10.4330/wjc.v17.i5.105670\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Dilated cardiomyopathy (DCM) is a common cause of systolic heart failure, and is the most prevalent type of non-ischemic cardiomyopathy. Primary hyperparathyroidism (PHPT) is characterized by hypercalcemia and excessive secretion of parathyroid hormone (PTH). Generally, PHPT is asymptomatic and is incidentally identified during routine laboratory assessments.</p><p><strong>Case summary: </strong>This case report details a 52-year-old man diagnosed with DCM and refractory hypercalcemia, who presented with clinical manifestations including dyspnea, recurrent anorexia, and abdominal distention. Laboratory investigations indicated an elevated serum PTH level, and the sestamibi scan suggested the presence of a parathyroid adenoma. Hence, the patient underwent a parathyroidectomy, which pathologically confirmed the diagnosis of a parathyroid adenoma. Postoperatively, the patient's hypercalcemia was corrected, the dimensions of the cardiac chambers were reduced, and there was a marked improvement in cardiac function.</p><p><strong>Conclusion: </strong>Our findings emphasize the importance of PTH assessment in patients with DCM and concurrent hypercalcemia.</p>\",\"PeriodicalId\":23800,\"journal\":{\"name\":\"World Journal of Cardiology\",\"volume\":\"17 5\",\"pages\":\"105670\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-05-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146955/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Cardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4330/wjc.v17.i5.105670\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Cardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4330/wjc.v17.i5.105670","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Reversible dilated cardiomyopathy caused by primary hyperparathyroidism: A case report.
Background: Dilated cardiomyopathy (DCM) is a common cause of systolic heart failure, and is the most prevalent type of non-ischemic cardiomyopathy. Primary hyperparathyroidism (PHPT) is characterized by hypercalcemia and excessive secretion of parathyroid hormone (PTH). Generally, PHPT is asymptomatic and is incidentally identified during routine laboratory assessments.
Case summary: This case report details a 52-year-old man diagnosed with DCM and refractory hypercalcemia, who presented with clinical manifestations including dyspnea, recurrent anorexia, and abdominal distention. Laboratory investigations indicated an elevated serum PTH level, and the sestamibi scan suggested the presence of a parathyroid adenoma. Hence, the patient underwent a parathyroidectomy, which pathologically confirmed the diagnosis of a parathyroid adenoma. Postoperatively, the patient's hypercalcemia was corrected, the dimensions of the cardiac chambers were reduced, and there was a marked improvement in cardiac function.
Conclusion: Our findings emphasize the importance of PTH assessment in patients with DCM and concurrent hypercalcemia.