Carolina Simões, Miguel Julião, Paula Câmara, Maria João Gomes, Maria Paula Custódio, Inês Goulão
{"title":"静脉注射英夫利昔单抗治疗癌症相关瘘管:家庭姑息治疗改善生活质量和闭合的病例报告","authors":"Carolina Simões, Miguel Julião, Paula Câmara, Maria João Gomes, Maria Paula Custódio, Inês Goulão","doi":"10.1080/15360288.2025.2517770","DOIUrl":null,"url":null,"abstract":"<p><p>Fistulae can severely impact a patient's quality of life, causing physical pain and excessive malodorous discharge. Beyond the physical symptoms, they also impose significant psychological and social burdens. This report presents a unique case involving the intravenous administration of a single dose of infliximab to a terminally ill patient with rectal adenocarcinoma complicated by severe enterocutaneous fistulae in the genital, subscrotal, and gluteal regions. This home-based intervention not only improved the patient's quality of life but also alleviated caregiver burdens and facilitated the timely completion of end-of-life tasks.</p>","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"408-412"},"PeriodicalIF":1.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Use of Intravenous Infliximab to Treat Cancer Related Fistulae: A Case Report in Home-Based Palliative Care Improving Quality of Life and Closure.\",\"authors\":\"Carolina Simões, Miguel Julião, Paula Câmara, Maria João Gomes, Maria Paula Custódio, Inês Goulão\",\"doi\":\"10.1080/15360288.2025.2517770\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Fistulae can severely impact a patient's quality of life, causing physical pain and excessive malodorous discharge. Beyond the physical symptoms, they also impose significant psychological and social burdens. This report presents a unique case involving the intravenous administration of a single dose of infliximab to a terminally ill patient with rectal adenocarcinoma complicated by severe enterocutaneous fistulae in the genital, subscrotal, and gluteal regions. This home-based intervention not only improved the patient's quality of life but also alleviated caregiver burdens and facilitated the timely completion of end-of-life tasks.</p>\",\"PeriodicalId\":16645,\"journal\":{\"name\":\"Journal of Pain & Palliative Care Pharmacotherapy\",\"volume\":\" \",\"pages\":\"408-412\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pain & Palliative Care Pharmacotherapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/15360288.2025.2517770\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pain & Palliative Care Pharmacotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/15360288.2025.2517770","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/11 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
The Use of Intravenous Infliximab to Treat Cancer Related Fistulae: A Case Report in Home-Based Palliative Care Improving Quality of Life and Closure.
Fistulae can severely impact a patient's quality of life, causing physical pain and excessive malodorous discharge. Beyond the physical symptoms, they also impose significant psychological and social burdens. This report presents a unique case involving the intravenous administration of a single dose of infliximab to a terminally ill patient with rectal adenocarcinoma complicated by severe enterocutaneous fistulae in the genital, subscrotal, and gluteal regions. This home-based intervention not only improved the patient's quality of life but also alleviated caregiver burdens and facilitated the timely completion of end-of-life tasks.