{"title":"双相躁狂症患者及其未受影响的一级亲属的心理理论和神经认知。","authors":"Jing Zeng, Tie-Bang Liu, Yang-Hui Liu","doi":"10.1002/jclp.70003","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment in manic patients involves neurocognitive and theory of mind (ToM) impairments. This study aims to investigate cognitive impairment among manic patients and their first-degree relatives (FDRs).</p><p><strong>Methods: </strong>A total of 31 manic inpatients, 31 unaffected relatives, and 30 healthy controls (HCs) were investigated using the Reading the Mind in Eye Test (RMET) and Hinting Task (HT). The intelligence quotient (IQ), attention, working memory, executive functions, fluency and processing speed were also assessed.</p><p><strong>Results: </strong>Patients and their relatives scored lower than controls on Theory of Mind reasoning and several neurocognitive measures. Regression analysis of the total sample indicated that a mania diagnosis or a FDR was strongly related to lower ToM reasoning performance. The deficits in ToM among patients were related to years of education.</p><p><strong>Conclusions: </strong>Due to the comparable performance of ToM between patients and their relatives, the reasoning aspect of ToM may represent a trait marker for bipolar disorder (BD). The deficits in ToM in patients with BD are partly independent of neurocognition.</p>","PeriodicalId":15395,"journal":{"name":"Journal of Clinical Psychology","volume":" ","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Theory of Mind and Neurocognition in Bipolar Mania Patients and Their Unaffected First-Degree Relatives.\",\"authors\":\"Jing Zeng, Tie-Bang Liu, Yang-Hui Liu\",\"doi\":\"10.1002/jclp.70003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Cognitive impairment in manic patients involves neurocognitive and theory of mind (ToM) impairments. This study aims to investigate cognitive impairment among manic patients and their first-degree relatives (FDRs).</p><p><strong>Methods: </strong>A total of 31 manic inpatients, 31 unaffected relatives, and 30 healthy controls (HCs) were investigated using the Reading the Mind in Eye Test (RMET) and Hinting Task (HT). The intelligence quotient (IQ), attention, working memory, executive functions, fluency and processing speed were also assessed.</p><p><strong>Results: </strong>Patients and their relatives scored lower than controls on Theory of Mind reasoning and several neurocognitive measures. Regression analysis of the total sample indicated that a mania diagnosis or a FDR was strongly related to lower ToM reasoning performance. The deficits in ToM among patients were related to years of education.</p><p><strong>Conclusions: </strong>Due to the comparable performance of ToM between patients and their relatives, the reasoning aspect of ToM may represent a trait marker for bipolar disorder (BD). The deficits in ToM in patients with BD are partly independent of neurocognition.</p>\",\"PeriodicalId\":15395,\"journal\":{\"name\":\"Journal of Clinical Psychology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Psychology\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1002/jclp.70003\",\"RegionNum\":3,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHOLOGY, CLINICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Psychology","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1002/jclp.70003","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
Theory of Mind and Neurocognition in Bipolar Mania Patients and Their Unaffected First-Degree Relatives.
Background: Cognitive impairment in manic patients involves neurocognitive and theory of mind (ToM) impairments. This study aims to investigate cognitive impairment among manic patients and their first-degree relatives (FDRs).
Methods: A total of 31 manic inpatients, 31 unaffected relatives, and 30 healthy controls (HCs) were investigated using the Reading the Mind in Eye Test (RMET) and Hinting Task (HT). The intelligence quotient (IQ), attention, working memory, executive functions, fluency and processing speed were also assessed.
Results: Patients and their relatives scored lower than controls on Theory of Mind reasoning and several neurocognitive measures. Regression analysis of the total sample indicated that a mania diagnosis or a FDR was strongly related to lower ToM reasoning performance. The deficits in ToM among patients were related to years of education.
Conclusions: Due to the comparable performance of ToM between patients and their relatives, the reasoning aspect of ToM may represent a trait marker for bipolar disorder (BD). The deficits in ToM in patients with BD are partly independent of neurocognition.
期刊介绍：
Founded in 1945, the Journal of Clinical Psychology is a peer-reviewed forum devoted to research, assessment, and practice. Published eight times a year, the Journal includes research studies; articles on contemporary professional issues, single case research; brief reports (including dissertations in brief); notes from the field; and news and notes. In addition to papers on psychopathology, psychodiagnostics, and the psychotherapeutic process, the journal welcomes articles focusing on psychotherapy effectiveness research, psychological assessment and treatment matching, clinical outcomes, clinical health psychology, and behavioral medicine.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
