成人眼眶-鼻肺泡横纹肌肉瘤的18F-FAPI PET/CT与18F-FDG PET/CT的比较

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-08-01 Epub Date: 2025-06-09 DOI:10.1097/RLU.0000000000005943

Hui Li, Lingge Suo, Jichao Zhou, Weifang Zhang, Yi Wang

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引用次数: 0

摘要

横纹肌肉瘤在儿童和青少年中很常见，但在成人中很少见。在这里，我们报告了一位41岁的眼眶-鼻肺泡横纹肌肉瘤患者，他接受了18F-FDG和18FAl-NOTA-FAPI PET/CT检查。与18F-FDG PET/CT轻度至中度摄取相比，18FAl-NOTA-FAPI PET/CT在原发病变和区域转移淋巴结显示强烈摄取，肿瘤与背景比良好。此外，18FAl-NOTA-FAPI PET/CT检测到18F-FDG PET/CT未发现的骨转移，这改变了患者的肿瘤分期和治疗策略。本病例提示18FAl-NOTA-FAPI PET/CT在评估成人眶-鼻肺泡横纹肌肉瘤方面可能优于18F-FDG PET/CT。

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18 F-FAPI PET/CT in An Adult Orbital-Nasal Alveolar Rhabdomyosarcoma: Comparisons With 18 F-FDG PET/CT.

Rhabdomyosarcoma is common in children and adolescents but rare in adults. Here, we presented a 41-year-old man with orbital-nasal alveolar rhabdomyosarcoma who underwent both 18 F-FDG and 18 FAl-NOTA-FAPI PET/CT. 18 FAl-NOTA-FAPI PET/CT showed intense uptake in the primary lesion and regional metastatic lymph nodes with an excellent tumor-to-background ratio, compared with the mild to moderate uptake on 18 F-FDG PET/CT. In addition, 18 FAl-NOTA-FAPI PET/CT detected bone metastases that were not identified by 18 F-FDG PET/CT, which altered the patient's tumor stage and treatment strategy. This case suggests that 18 FAl-NOTA-FAPI PET/CT maybe superior to 18 F-FDG PET/CT in the assessment of adult orbital-nasal alveolar rhabdomyosarcoma.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.