心脏移植和持久机械循环支持治疗特殊不常见的心肌病

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

CJC Open Pub Date : 2025-06-01 DOI:10.1016/j.cjco.2025.03.015

Ana Roussoulières MD, PhD , Marta Farrero MD, PhD , Finn Gustafsson MD, PhD , Michelle Kittleson MD, PhD , Mrudula Munagala MD , Josef Stehlik MD, MPH

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引用次数: 0

摘要

在非典型病因特异性心肌病患者中，与传统的缺血性和扩张性心肌病患者一样，进展性心衰的临床特征没有很好的定义，需要进行晚期心衰（AHF）治疗。其中一些特定的心肌病与全身性疾病有关，心外受累的影响和严重程度对于确定AHF治疗的适当选择至关重要。这篇综述的重点是在特殊原因的心肌病，如肥厚性心肌病，心脏结节病，心脏淀粉样变性和心律失常性右室心肌病的特殊注意事项。该综述评估了AHF治疗，包括心脏移植和耐用的机械循环支持装置，以及这些患者在接受AHF治疗后的管理差异。

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Heart Transplant and Durable Mechanical Circulatory Support for Specific Less-Common Cardiomyopathies

Clinical characteristics of progressive heart failure warranting advanced heart failure (AHF) therapies are not well defined in patients with atypical cause-specific cardiomyopathies, as in conventional ischemic and dilated cardiomyopathies. Some of these specific cardiomyopathies are associated with systemic diseases, and the impact and the severity of extracardiac involvement is crucial in defining the appropriate choice of AHF therapies. This review focuses on special considerations in cause-specific cardiomyopathies, such as hypertrophic cardiomyopathy, cardiac sarcoidosis, cardiac amyloidosis, and arrhythmogenic right ventricular cardiomyopathy. The review evaluates AHF therapies, including heart transplantation and durable mechanical circulatory support devices, along with nuances in the management of these patients after they receive AHF therapies.

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