苯丙酸酯在283.15 ~ 323.15 K 12种纯溶剂中的溶解度测定和热力学模型

IF 2 3区 工程技术 Q3 CHEMISTRY, MULTIDISCIPLINARY
Jingxuan Qiu*, Rui Zhang, Chaoqun Zhang, Jing Lin, Cong Liu, Yunchun Guo, Huiliang Wang, Yingxin Xie and Ke Xiao, 
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引用次数: 0

摘要

在283.15 ~ 323.15 K的常压下,用静态重量法测定了苯丙酸酯在水、丙酮、2-丁酮、乙酸甲酯、乙酸乙酯、甲醇、乙醇、正丙醇、异丙醇、正丁醇、仲丁醇和1-戊醇中的溶解度。溶解度随温度的升高而单调增加。其溶解度大致为丙酮>;甲基乙基酮;醋酸甲酯;乙酸乙酯>;非酒精溶剂和甲醇中的水;1-pentanol祝辞进行比;乙醇比;正丁醇的在正丙醇比;醇中的异丙醇。苯丙酸盐的溶解度最终取决于溶剂极性、氢键受体倾向、溶剂-溶剂分子间相互作用和空间位阻的综合影响。此外,通过Apelblat模型和Yaws模型对溶解度数据进行了相关性分析。结果表明,两种模型均能较好地拟合实验数据,其中Yaws模型比Apelblat模型更适合于关联苯丙酸盐的溶解度。本工作所报道的数据有助于苯丙酸酯的进一步结晶和分离工艺。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Solubility Determination and Thermodynamic Modeling of Phenprobamate in 12 Pure Solvents from 283.15 to 323.15 K

Solubility Determination and Thermodynamic Modeling of Phenprobamate in 12 Pure Solvents from 283.15 to 323.15 K

In this work, the solubility of phenprobamate in water, acetone, 2-butanone, methyl acetate, ethyl acetate, methanol, ethanol, n-propanol, isopropanol, n-butanol, sec-butanol, and 1-pentanol was determined by a static gravimetric method at temperatures ranging from 283.15 to 323.15 K under atmospheric pressure. The solubility magnitudes increase monotonously with the increase of temperature in each solvent. The solubility is roughly ranked as propanone > methyl ethyl ketone > acetic acid methyl ester > ethyl acetate > water in non-alcohol solvents and methanol > 1-pentanol > sec-butanol > ethanol > n-butanol > n-propanol > isopropanol in alcohols. The solubility of phenprobamate could be ultimately determined by the combined influence of solvent polarity, hydrogen bond acceptor propensities, solvent–solvent intermolecular interactions, and spatial steric hindrance. In addition, the solubility data were correlated by the Apelblat model and the Yaws model. The outcomes show that the two models could both satisfactorily fit the experimental data, in which the Yaws model is more appropriate to correlate the solubility of phenprobamate compared with the Apelblat model. The data reported in this work contribute to the further crystallization and separation process of phenprobamate.

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来源期刊
Journal of Chemical & Engineering Data
Journal of Chemical & Engineering Data 工程技术-工程:化工
CiteScore
5.20
自引率
19.20%
发文量
324
审稿时长
2.2 months
期刊介绍: The Journal of Chemical & Engineering Data is a monthly journal devoted to the publication of data obtained from both experiment and computation, which are viewed as complementary. It is the only American Chemical Society journal primarily concerned with articles containing data on the phase behavior and the physical, thermodynamic, and transport properties of well-defined materials, including complex mixtures of known compositions. While environmental and biological samples are of interest, their compositions must be known and reproducible. As a result, adsorption on natural product materials does not generally fit within the scope of Journal of Chemical & Engineering Data.
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