更年期和身体组成:一个复杂的领域。

IF 1.9 3区 医学 Q3 OBSTETRICS & GYNECOLOGY
Hanna-Kaarina Juppi, Jari E Karppinen, Eija K Laakkonen
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引用次数: 0

摘要

鉴于更年期影响了世界上大约一半的中年人口,了解其影响超越传统的更年期症状是至关重要的。例如,许多女性在经历更年期的过渡期间,身体成分发生了深刻的变化。这些变化可能有助于绝经后代谢健康的降低。这篇叙述性综述探讨了更年期对骨骼肌和脂肪组织的影响,强调了肌肉质量和力量的下降以及脂肪组织的增加和重新分配,特别是内脏脂肪的增加。尽管绝经期身体成分的变化似乎得到了广泛的研究,但纵向研究并不常见,驱动身体成分变化的确切机制仍不清楚,与常规衰老、能量平衡和生活方式因素相比,激素变化的作用仍不确定。值得注意的是,更年期或雌激素是否会影响静息能量消耗仍存在争议。该综述还考虑了更年期激素治疗和定期锻炼的潜在缓解作用。了解这些变化对于制定有效战略以支持妇女在绝经期间和绝经后的健康至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Menopause and Body Composition: A Complex Field.

Given that menopause affects about half of the world's midlife population, it is crucial to understand its impact beyond traditional menopausal symptomology. For instance, many women, while transitioning through menopause, experience profound changes in body composition. These changes may contribute to postmenopausal reductions in metabolic health. This narrative review explores the influence of menopause on skeletal muscle and adipose tissue, highlighting the decline in muscle mass and strength and the gain and redistribution of adipose tissue, particularly the increase in visceral adiposity. Although menopausal changes in body composition are seemingly extensively studied, the longitudinal studies are not that common, and the precise mechanisms driving body composition changes remain unclear, with uncertainties surrounding the roles of hormonal shifts compared with regular aging, energy balance, and lifestyle factors. Notably, it remains debated whether menopause or estrogen meaningfully influences resting energy expenditure. The review also considers the potential mitigating effects of menopausal hormone therapy and regular exercise. Understanding these changes is essential for developing effective strategies to support women's health during and after menopause.

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来源期刊
Seminars in reproductive medicine
Seminars in reproductive medicine 医学-妇产科学
CiteScore
5.80
自引率
0.00%
发文量
24
审稿时长
6-12 weeks
期刊介绍: Seminars in Reproductive Medicine is a bi-monthly topic driven review journal that provides in-depth coverage of important advances in the understanding of normal and disordered human reproductive function, as well as new diagnostic and interventional techniques. Seminars in Reproductive Medicine offers an informed perspective on issues like male and female infertility, reproductive physiology, pharmacological hormonal manipulation, and state-of-the-art assisted reproductive technologies.
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