自体移植物与同种异体骨髓吸液作为截骨间隙填充物在进行性塌陷扁平足畸形侧柱延长中的应用。

Foot & Ankle Orthopaedics Pub Date : 2025-06-08 eCollection Date: 2025-04-01 DOI:10.1177/24730114251342580
Ramesh Radhakrishnan, Don Thong Siang Koh, Eric Wei Liang Cher, Wenxian Png, Inderjeet Rikhraj Singh
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引用次数: 0

摘要

背景:进行性塌陷扁平足畸形(PCFD)是一种以后足外翻、足中内翻和前足外展为特征的复杂疾病,可导致功能损害和疼痛。手术矫正通常包括侧柱延长(LCL),它可以解决结构畸形并恢复排列。尽管供体部位存在并发症,自体移植物仍然是LCL截骨间隙填充物的金标准。同种异体移植物增强患者自己的骨髓抽液浓缩物(BMAC)提供了一个潜在的替代,因为他们的成骨特性。本研究比较了自体移植物与同种异体移植物联合BMAC在PCFD LCL中的临床和影像学结果。方法:本回顾性研究回顾了2012年至2022年在某高等院校接受PCFD LCL治疗的38例患者。患者分为2组:自体移植25例(A组),同种异体移植混合BMAC 13例(B组)。临床结果采用视觉模拟量表(VAS)、美国骨科足踝协会(AOFAS)踝关节-后足评分和36项简短健康调查(SF-36)评分,分别于术后6个月和24个月进行评估。术后定期通过系列负重x线片评估放射愈合。结果:A组和B组均达到放射愈合,平均时间分别为5.64±1.80和5.15±2.58个月。没有延迟愈合或不愈合的病例。两组在6个月和24个月时VAS、AOFAS和SF-36评分均有显著改善,结果无统计学差异。A组腓骨肌腱病变2例,腓骨肌腱与钢板粘连1例,螺钉突出1例,足底神经刺激引起慢性疼痛1例。B组无并发症报告。结论:本研究表明,BMAC增强同种异体移植物可能是PCFD中LCL的可行替代自体移植物,可提供相似的愈合率和功能结果。然而,作为一项样本量较小的回顾性队列研究,需要进一步的前瞻性研究来证实这些发现。证据等级:III级,回顾性队列研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Autograft vs Allograft With Bone Marrow Aspirate Concentrate as an Osteotomy Gap Filler in Lateral Column Lengthening for Progressive Collapsing Flatfoot Deformity.

Autograft vs Allograft With Bone Marrow Aspirate Concentrate as an Osteotomy Gap Filler in Lateral Column Lengthening for Progressive Collapsing Flatfoot Deformity.

Autograft vs Allograft With Bone Marrow Aspirate Concentrate as an Osteotomy Gap Filler in Lateral Column Lengthening for Progressive Collapsing Flatfoot Deformity.

Autograft vs Allograft With Bone Marrow Aspirate Concentrate as an Osteotomy Gap Filler in Lateral Column Lengthening for Progressive Collapsing Flatfoot Deformity.

Background: Progressive collapsing flatfoot deformity (PCFD) is a complex condition characterized by hindfoot valgus, midfoot varus, and forefoot abduction, leading to functional impairment and pain. Surgical correction often includes lateral column lengthening (LCL), which addresses structural deformity and restores alignment. Autografts remain the gold standard as an osteotomy gap filler for LCL despite donor site morbidity. Allografts augmented with patient's own bone marrow aspirate concentrate (BMAC) offer a potential alternative because of their osteogenic properties. This study compares the clinical and radiologic outcomes of autografts vs allografts with BMAC in LCL for PCFD.

Methods: This retrospective study reviewed 38 patients who underwent LCL for PCFD at a tertiary institution from 2012 to 2022. Patients were divided into 2 groups: the 25 who received autografts (group A), and the 13 who received allografts (group B) mixed with BMAC. Clinical outcomes were assessed using visual analog scale (VAS), American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot scores, and 36-Item Short Form Health Survey (SF-36) scores at 6 and 24 months postoperatively. Radiologic union was evaluated through serial weightbearing radiographs at regular interval post-surgery.

Results: Both groups A and B achieved radiologic union at an average of 5.64 ± 1.80 and 5.15 ± 2.58 months, respectively. There were no cases of delayed union or nonunion. Both groups demonstrated significant improvements in VAS, AOFAS, and SF-36 scores at 6 and 24 months, with no statistically significant differences in outcomes. Group A had 2 cases of peroneal tendinopathy, 1 case of peroneal tendon adhesion to the plate, 1 case of screw prominence, and 1 case of chronic pain attributed to plantar nerve irritation. Group B had no reported complications.

Conclusion: This study suggests that allografts augmented with BMAC may be a viable alternative to autografts for LCL in PCFD, offering comparable union rates and functional outcomes. However, as a retrospective cohort study with a small sample size, further prospective research is needed to confirm these findings.

Level of evidence: Level III, retrospective cohort studies.

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Foot & Ankle Orthopaedics
Foot & Ankle Orthopaedics Medicine-Orthopedics and Sports Medicine
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