肾移植术后手术并发症。

IF 1.4 4区 医学 Q3 SURGERY
Tímea Blichová, Patrícia Kleinová, Matej Vnučák, Karol Graňák, Andrej Kollár, Jan Svihra, Juraj Miklušica, Ivana Dedinská
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引用次数: 0

摘要

肾移植是终末期肾病患者的最佳治疗选择。尽管手术技术有所进步,但手术本身仍存在术后并发症的风险,发生率为5-25%。本回顾性分析的目的是确定肾移植术后手术并发症的危险因素。材料和方法本研究纳入了283例11年(2013-2023年)期间在本中心接受肾移植的患者。记录受者的基线特征(年龄、性别、供体类型)和影响手术并发症发生的因素(诱导治疗类型、糖尿病、BK阳性)。确定并分析发生手术并发症(出血、淋巴囊肿、输尿管狭窄)的患者与潜在独立危险因素的关系。结果15.8%的患者(n=45)出现手术并发症,输尿管狭窄占所有手术并发症的60%。手术并发症发生的平均时间为5.4 ~ 8.6个月。通过Cox比例风险回归多变量分析,没有发现任何参数是手术并发症发生的独立危险因素(终点:手术并发症本身、出血、输尿管狭窄、淋巴囊肿/淋巴漏)。结论肾移植可显著改善终末期肾病患者的生活质量和生存。手术并发症仍然是移植后的一个重大挑战,泌尿、血管和顶骨并发症是最常见的。虽然我们在研究的参数中没有发现独立的危险因素,但最小化这些并发症对于减少再干预的需要和改善结果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical Complications After Kidney Transplantation.

BACKGROUND Kidney transplantation is the best therapeutic option for patients with end-stage kidney disease. Despite advances in surgical techniques, the surgical procedure itself is associated with a risk of postoperative complications, with an incidence rate of 5-25%. The aim of this retrospective analysis was to identify risk factors for surgical complications after kidney transplantation. MATERIAL AND METHODS The study included 283 patients who underwent kidney transplantation at our center over an 11-year period (2013-2023). Baseline characteristics of the recipients (age, sex, and type of donor) and factors influencing the development of surgical complications (type of induction therapy, diabetes mellitus, BK positivity) were recorded. Patients who developed a surgical complication (bleeding, lymphocele, ureteral stenosis) were identified and analyzed in relation to potential independent risk factors. RESULTS Surgical complications occurred in 15.8% of patients (n=45), with ureteral stenosis comprising 60% of all surgical complications. The average time to surgical complication onset ranged from 5.4 to 8.6 months. By using Cox proportional-hazard regression multivariate analysis, none of the parameters that were looked at were found to be independent risk factors for the development of surgical complications (endpoints: surgical complications itself, bleeding, ureteral stenosis, lymphocele/lymphorrhea). CONCLUSIONS Kidney transplantation significantly improves quality of life and survival in patients with end-stage kidney disease. Surgical complications remain a significant post-transplant challenge, with urological, vascular, and parietal complications being most common. While we found no independent risk factors among the parameters studied, minimizing these complications is essential to reduce the need for reinterventions and to improve outcomes.

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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation. Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication. Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
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