高危PET:拯救生命的干预主义方法。案例报告和文献综述

Hernan Yair Florez de Moya , Luis Alfonso Bustamante-Cristancho , Adalberto de Jesus Caro
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引用次数: 0

摘要

我们报告一例年轻患者在心脏骤停(停搏)后入院,在有创机械通气下复苏15分钟,入院时血液动力学不稳定,心房颤动节律伴心室快速反应。在心脏骤停的潜在原因中,怀疑肺血栓栓塞和药物滥用(由于不知道转诊部位的确切病史),POCUS行时有明显的右心室受累和当时DVT的CUS阴性的证据,因此通过正式的经胸超声心动图和紧急胸部血管断层扫描证实心脏受累,显示双侧大叶和节段分支受累。在这种情况下,根据目前的治疗指南,大量PTE被认为有溶栓治疗的适应症,然而,考虑到有创性手术机构的可用性,通过抽吸进行部分取栓,减少血栓负荷,动脉内输注溶栓(西雅图方案),通过肺动脉干导管,除了输注未分离的肝素外,还可以进行动脉内输注溶栓。患者的临床进展良好,最初在ICU住院3天,随后出院到普通医院,鉴于SAF阴性,确定口服DOAC抗凝。通过这种方式,我们展示了一种对日益频繁和潜在致命的病理进行强化管理的形式,减轻了与系统性溶栓相关的风险,如脑出血,这可能发生在高达10%的病例中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TEP de alto riesgo: abordaje intervencionista que salva vidas. Reporte de caso y revisión de literatura
We report the case of a young patient admitted to our institution after suffering cardiac arrest (asystole) and being resuscitated for 15 minutes, under invasive mechanical ventilation, with hemodynamic lability and atrial fibrillation rhythm with rapid ventricular response upon admission. Among the potential causes of cardiac arrest, pulmonary thromboembolism and drug abuse were suspected (due to not knowing the exact history of the referral site), POCUS was performed with evidence of significant right ventricular involvement and negative CUS at that time for DVT, so cardiac involvement was confirmed with formal transthoracic echocardiogram and urgent chest angiotomography, which showed bilateral involvement of lobar and segmental branches. In this context, massive PTE is considered with indication for thrombolytic management according to current management guidelines, however, given the availability in the institution of invasive procedure, partial thrombectomy is performed by aspiration reducing the thrombotic load and intra-arterial infusion thrombolysis is left (Seattle Protocol), through a catheter in the trunk of the pulmonary artery, in addition to infusion of unfractionated heparin. The clinical evolution of the patient was favorable, with initial stay in ICU for 3 days and subsequent discharge to general hospitalization where oral anticoagulation with DOAC was defined in view of the negative profile for SAF. In this way we demonstrate a form of intensive management of an increasingly frequent and potentially fatal pathology, mitigating the risks associated with systemic thrombolysis such as intracerebral bleeding, which can occur in up to 10% of cases.
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