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锌(II)-金属光抗生素：实验和计算方法确定抗菌和抗生物膜应用的治疗作用

IF 4.2 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Chemical Communications Pub Date : 2025-06-06 DOI:10.1039/d5cc02340h
Rajesh Kushwaha , Sangeeta Kumari , Arya Mishra , Anjali Upadhyay , Archana Rai , Malay Nayak , Sudip Mukherjee , Samya Banerjee
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引用次数: 0

摘要

报道了基于姜黄素的新型锌（II）金属光抗生素对大肠杆菌和枯草芽孢杆菌的抑菌效果。计算机研究表明了它们的ROS生成能力和与细菌蛋白的结合相互作用。结果表明，锌(II)-金属光抗生素在抗菌光动力治疗中具有优势。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

Zn(ii)-metallo-photoantibiotics: experimental and computational approach identifying a therapeutic role for antibacterial and antibiofilm applications†

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Zn(ii)-metallo-photoantibiotics: experimental and computational approach identifying a therapeutic role for antibacterial and antibiofilm applications†
The antibacterial profiles of curcumin-based novel Zn(ii)-metallo-photoantibiotics against E. coli and B. subtilis are reported. In silico studies indicated their ROS generation capacity and binding interaction with bacterial proteins. Therapeutic results indicated the advantages of these Zn(ii)-metallo-photoantibiotics in antibacterial photodynamic therapy.
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来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
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