Darae Kim, In-Cheol Kim, Jong-Chan Youn, Jin-Jin Kim, Mi-Hyang Jung, Jin-Oh Choi, Daniel Seong Kyu Kim, Mason Lee, Evan P Kransdorf, David H Chang, Michelle M Kittleson, Michele Hamilton, Jignesh K Patel, Fardad Esmailian, Jon A Kobashigawa
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Among them, 15 patients underwent BaS, and their clinical trajectories were compared with 62 patients with advanced HF who received orthotopic heart transplant (OHT) or durable mechanical circulatory support without BaS (non-BaS group) during the same period. Key outcomes included BMI reduction, OHT eligibility, and post-OHT survival.</p><p><strong>Results: </strong>Among 15 patients who underwent BaS, 12 underwent sleeve gastrectomy and 3 underwent gastric bypass surgery. After a median duration of 11 (6-14) months from BaS, the mean value of BMI was significantly reduced (39.8 [39.0-42.2] kg/m<sup>2</sup> versus 31.6 [27.7-35.3] kg/m<sup>2</sup>, P < .001) with no BaS related mortality. In subgroup of OHT patients, post-OHT survival was comparable between the 2 groups.</p><p><strong>Conclusions: </strong>BaS is a safe and effective intervention for BMI reduction in patients with advanced HF. BaS may enhance OHT eligibility without compromising posttransplantation outcomes.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of bariatric surgery in patients with advanced heart failure.\",\"authors\":\"Darae Kim, In-Cheol Kim, Jong-Chan Youn, Jin-Jin Kim, Mi-Hyang Jung, Jin-Oh Choi, Daniel Seong Kyu Kim, Mason Lee, Evan P Kransdorf, David H Chang, Michelle M Kittleson, Michele Hamilton, Jignesh K Patel, Fardad Esmailian, Jon A Kobashigawa\",\"doi\":\"10.1016/j.soard.2025.05.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Although bariatric surgery (BaS) is an important treatment option to treat obesity in general, the safety and efficacy of BaS in patients with advanced heart failure (HF) are not well known.</p><p><strong>Objectives: </strong>To describe the trajectory of patients with advanced HF who underwent BaS and cardiac replacement therapy.</p><p><strong>Setting: </strong>Single-tertiary academic hospital.</p><p><strong>Methods: </strong>We conducted a retrospective study of patients with advanced HF with obesity (body mass index [BMI] >35 kg/m<sup>2</sup>) between January 2010 and August 2022. 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引用次数: 0
摘要
背景：虽然减肥手术（BaS）通常是治疗肥胖的重要治疗选择，但BaS在晚期心力衰竭（HF）患者中的安全性和有效性尚不清楚。目的：描述晚期心衰患者接受BaS和心脏替代治疗的轨迹。单位：一所三级学术医院。方法：我们对2010年1月至2022年8月期间伴有肥胖（体重指数[BMI] bbb35 kg/m2）的晚期心衰患者进行了回顾性研究。其中15例患者接受了BaS，并将其临床轨迹与同期62例接受原位心脏移植（OHT）或无BaS的耐用机械循环支持的晚期HF患者（非BaS组）进行比较。主要结局包括BMI降低、OHT适格性和OHT后生存。结果：15例BaS患者中，12例行袖胃切除术，3例行胃分流术。BaS的中位持续时间为11（6-14）个月后，BMI平均值显著降低（39.8 [39.0-42.2]kg/m2比31.6 [27.7-35.3]kg/m2, P < 0.001），无BaS相关死亡率。在OHT患者亚组中，两组之间的OHT后生存率具有可比性。结论：BaS是降低晚期心衰患者BMI的一种安全有效的干预措施。BaS可以在不影响移植后结果的情况下提高OHT的适格性。
Role of bariatric surgery in patients with advanced heart failure.
Background: Although bariatric surgery (BaS) is an important treatment option to treat obesity in general, the safety and efficacy of BaS in patients with advanced heart failure (HF) are not well known.
Objectives: To describe the trajectory of patients with advanced HF who underwent BaS and cardiac replacement therapy.
Setting: Single-tertiary academic hospital.
Methods: We conducted a retrospective study of patients with advanced HF with obesity (body mass index [BMI] >35 kg/m2) between January 2010 and August 2022. Among them, 15 patients underwent BaS, and their clinical trajectories were compared with 62 patients with advanced HF who received orthotopic heart transplant (OHT) or durable mechanical circulatory support without BaS (non-BaS group) during the same period. Key outcomes included BMI reduction, OHT eligibility, and post-OHT survival.
Results: Among 15 patients who underwent BaS, 12 underwent sleeve gastrectomy and 3 underwent gastric bypass surgery. After a median duration of 11 (6-14) months from BaS, the mean value of BMI was significantly reduced (39.8 [39.0-42.2] kg/m2 versus 31.6 [27.7-35.3] kg/m2, P < .001) with no BaS related mortality. In subgroup of OHT patients, post-OHT survival was comparable between the 2 groups.
Conclusions: BaS is a safe and effective intervention for BMI reduction in patients with advanced HF. BaS may enhance OHT eligibility without compromising posttransplantation outcomes.
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