Shruti P Shertukde, Ramya Padmanabha, Stephanie T Chung, Claire Gaudichon, Kerry S Jones, Paul Kelly, Nancy F Krebs, Anura Kurpad, Yvonne Lamers, Veronica Lopez-Teros, Alida Melse-Boonstra, Fatima C Pereira, Carla M Prado, Susan B Roberts, John Shepherd, Pattanee Winichagoon, Jonathan C K Wells, Cornelia U Loechl, Daniel J Hoffman
{"title":"为改进行动铺平道路:核技术如何促进营养不良评估。","authors":"Shruti P Shertukde, Ramya Padmanabha, Stephanie T Chung, Claire Gaudichon, Kerry S Jones, Paul Kelly, Nancy F Krebs, Anura Kurpad, Yvonne Lamers, Veronica Lopez-Teros, Alida Melse-Boonstra, Fatima C Pereira, Carla M Prado, Susan B Roberts, John Shepherd, Pattanee Winichagoon, Jonathan C K Wells, Cornelia U Loechl, Daniel J Hoffman","doi":"10.1016/j.ajcnut.2025.06.003","DOIUrl":null,"url":null,"abstract":"<p><p>Malnutrition in all its forms-including undernutrition, micronutrient deficiencies, and overnutrition-continues to rise globally, driven by complex structural and biological factors that contribute to an increased risk of noncommunicable diseases (NCDs). Addressing this multifaceted challenge requires precise assessment tools. To advance this effort, the International Atomic Energy Agency held a technical meeting of global experts to explore how nuclear techniques, specifically stable isotope tracers and imaging methods, and emerging technologies can enhance nutrition assessments to better address malnutrition. On the basis of the meeting's discussions, this report highlights the application of nuclear techniques to improve the measurement of body composition across life stages and disease states, assess nutrient bioavailability more holistically, elucidate nutrient flux under conditions of malnutrition, trace metabolic processes linked to NCDs, and refine nutrient requirements to better reflect diverse populations. The integration of nuclear techniques with emerging tools such as artificial intelligence and model-based compartmental analysis was emphasized as a key strategy to enhance their utility. This report also highlights the important role of nuclear techniques in addressing malnutrition and calls for interdisciplinary collaboration and reduced research silos to fully leverage these techniques to combat this condition more effectively.</p>","PeriodicalId":50813,"journal":{"name":"American Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":6.5000,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Paving the way for improved action: how nuclear techniques can advance the assessment of malnutrition.\",\"authors\":\"Shruti P Shertukde, Ramya Padmanabha, Stephanie T Chung, Claire Gaudichon, Kerry S Jones, Paul Kelly, Nancy F Krebs, Anura Kurpad, Yvonne Lamers, Veronica Lopez-Teros, Alida Melse-Boonstra, Fatima C Pereira, Carla M Prado, Susan B Roberts, John Shepherd, Pattanee Winichagoon, Jonathan C K Wells, Cornelia U Loechl, Daniel J Hoffman\",\"doi\":\"10.1016/j.ajcnut.2025.06.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Malnutrition in all its forms-including undernutrition, micronutrient deficiencies, and overnutrition-continues to rise globally, driven by complex structural and biological factors that contribute to an increased risk of noncommunicable diseases (NCDs). 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Paving the way for improved action: how nuclear techniques can advance the assessment of malnutrition.
Malnutrition in all its forms-including undernutrition, micronutrient deficiencies, and overnutrition-continues to rise globally, driven by complex structural and biological factors that contribute to an increased risk of noncommunicable diseases (NCDs). Addressing this multifaceted challenge requires precise assessment tools. To advance this effort, the International Atomic Energy Agency held a technical meeting of global experts to explore how nuclear techniques, specifically stable isotope tracers and imaging methods, and emerging technologies can enhance nutrition assessments to better address malnutrition. On the basis of the meeting's discussions, this report highlights the application of nuclear techniques to improve the measurement of body composition across life stages and disease states, assess nutrient bioavailability more holistically, elucidate nutrient flux under conditions of malnutrition, trace metabolic processes linked to NCDs, and refine nutrient requirements to better reflect diverse populations. The integration of nuclear techniques with emerging tools such as artificial intelligence and model-based compartmental analysis was emphasized as a key strategy to enhance their utility. This report also highlights the important role of nuclear techniques in addressing malnutrition and calls for interdisciplinary collaboration and reduced research silos to fully leverage these techniques to combat this condition more effectively.
期刊介绍:
American Journal of Clinical Nutrition is recognized as the most highly rated peer-reviewed, primary research journal in nutrition and dietetics.It focuses on publishing the latest research on various topics in nutrition, including but not limited to obesity, vitamins and minerals, nutrition and disease, and energy metabolism.
Purpose:
The purpose of AJCN is to:
Publish original research studies relevant to human and clinical nutrition.
Consider well-controlled clinical studies describing scientific mechanisms, efficacy, and safety of dietary interventions in the context of disease prevention or health benefits.
Encourage public health and epidemiologic studies relevant to human nutrition.
Promote innovative investigations of nutritional questions employing epigenetic, genomic, proteomic, and metabolomic approaches.
Include solicited editorials, book reviews, solicited or unsolicited review articles, invited controversy position papers, and letters to the Editor related to prior AJCN articles.
Peer Review Process:
All submitted material with scientific content undergoes peer review by the Editors or their designees before acceptance for publication.