肿瘤凝固组推进肿瘤精准手术。

IF 14.3 1区医学 Q1 ONCOLOGY

Trends in cancer Pub Date : 2025-06-06 DOI:10.1016/j.trecan.2025.05.006

Antoine Galmiche, Zuzana Saidak, Cliona C Kirwan

引用次数: 0

摘要

实体肿瘤产生局部和全身的促凝状态，使癌症患者面临止血并发症的风险。肿瘤凝血组（肿瘤固有的决定因素）和手术引起的凝血功能障碍之间的相互作用可能影响完全手术切除后复发的风险。围手术期靶向凝血组可推进肿瘤精准治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advancing cancer precision surgery with the tumor coagulome.

Solid tumors generate a local and systemic procoagulant state, placing cancer patients at risk of hemostatic complications. The interplay between the tumor coagulome, a tumor-intrinsic determinant, and surgery-induced coagulopathy may influence the risk of recurrence following complete surgical resection. Perioperative targeting of the coagulome could advance cancer precision treatment.

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来源期刊

Trends in cancer Medicine-Oncology

CiteScore

28.50

自引率

0.50%

发文量

138

期刊介绍： Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.