自体骨与牛骨矿物质联合自体骨芯片两期上颌窦底增强术后骨尺寸稳定性分析：来自1年多中心裂口随机对照试验的结果。

IF 4.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of dentistry Pub Date : 2025-06-06 DOI:10.1016/j.jdent.2025.105889

Isabella Neme Ribeiro dos Reis , Anouck Jue , Eppo Wolvius , Justin Pijpe , Rubens Spin-Neto , Ronald Ernest Jung , Nadja Naenni , Franz J. Strauss , Brend Jonker

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引用次数: 0

摘要

目的：比较上颌窦底增强术（MSFA）一年后自体骨（AB）与牛骨矿物联合局部采集的AB骨片（BBM）的尺寸稳定性。材料和方法：对20例患者（40颗种植体）进行了一项多中心随机对照试验的二次分析。CBCT/ ct在种植体放置前（msfa后4-6个月，T1）和种植体加载后12个月（T2）两个时间点测量种植体中心的骨高度（颊部和腭部）和骨面积。距嵴1、5和10 mm处的残余骨高度和窦宽度也被记录下来。采用广义估计方程（GEE）的线性回归模型评估接枝材料（AB和BBM）、初始接枝尺寸和鼻窦宽度对尺寸变化的影响。结果：调整后的回归模型显示，经ab处理的部位移植物高度明显降低(颊部平均差异：-1.76 mm [95%CI, -0.86至-2.65]；p值 = 结论：使用BBM联合自体骨芯片的MSFA比单独使用AB具有更大的尺寸稳定性。临床意义：BBM联合自体芯片比单独使用AB能更好地保存移植物尺寸。

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Analysis of bone dimensional stability after two-stage maxillary sinus floor augmentation with autogenous bone versus bovine bone mineral combined with autogenous bone chips: results from a 1-year multicenter split-mouth randomized controlled trial

Objective

To compare the dimensional stability of augmented bone following maxillary sinus floor augmentation (MSFA) using autogenous bone (AB) alone or bovine bone mineral combined with locally harvested AB chips (BBM), one year after implant loading.

Material and methods

A secondary analysis of a split-mouth, multicenter randomized controlled trial was conducted among 20 patients (40 implants). CBCT/CTs were used to measure bone height (buccal and palatal aspects) and bone area at the implant center at two time points: before implant placement (4–6 months post-MSFA, T1) and 12 months post-implant loading (T2). Residual bone height and sinus width at 1, 5, and 10 mm from the crest were also recorded. Linear regression models with generalized estimating equations were used to assess the influence of graft material (AB and BBM), initial graft dimensions and sinus width on dimensional changes.

Results

Adjusted regression models showed that AB-treated sites experienced significantly greater reductions in graft height (mean difference at buccal sites: -1.76 mm [95 % CI, -0.86 to -2.65]; p-value = <0.001); mean difference at palatal sites: -1.82 mm [95 % CI -0.75 to -2.88]; p = 0.001; and bone area (mean difference –17.80 mm² [95 % CI –6.61 to –28.99]; p = 0.002) compared to BBM. Greater initial graft height and area were associated with reduced dimensional changes (p < 0.001) especially when using BBM. Sinus width, measured 10 mm from the crest, was modestly but significantly associated with changes in bone height (p = 0.020), but not with changes in bone area (p = 0.147).

Conclusion

MSFA using BBM combined with autogenous bone chips resulted in greater dimensional stability compared to AB alone.

Clinical implications

BBM combined with autogenous bone chips better preserved graft dimensions than AB alone.

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来源期刊

Journal of dentistry 医学-牙科与口腔外科

CiteScore

7.30

自引率

11.40%

发文量

349

审稿时长

35 days

期刊介绍： The Journal of Dentistry has an open access mirror journal The Journal of Dentistry: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The Journal of Dentistry is the leading international dental journal within the field of Restorative Dentistry. Placing an emphasis on publishing novel and high-quality research papers, the Journal aims to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. Topics covered include the management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research. The Journal of Dentistry will publish original scientific research papers including short communications. It is also interested in publishing review articles and leaders in themed areas which will be linked to new scientific research. Conference proceedings are also welcome and expressions of interest should be communicated to the Editor.