维生素输送纳米技术的新趋势:创新和未来前景

Md. Sumon Miah , Md. Waziur Rahman Chy , Tanvir Ahmed , Mahjabin Suchi , Md. Awwal Muhtady , Shah Nizam Uddin Ahmad , Mohammad Afzal Hossain
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引用次数: 0

摘要

纳米技术已经成为改善维生素输送系统的前沿方法,解决了诸如低溶解度、不稳定性和有限的生物利用度等关键挑战。传统的维生素制剂经常受到快速降解和吸收效率低下的挑战,从而降低了其有效性。整合纳米载体——包括聚合纳米颗粒、脂基纳米颗粒、金属基系统、脂质体和纳米乳液——已证明在增强维生素稳定性和控制释放、优化体内营养吸收方面具有重大潜力。本文综述了纳米技术在维生素递送中的各种应用,强调了各种纳米载体体系的优势。它讨论了纳米级递送平台如何改善维生素保护,溶解度和吸收,潜在地导致更有效的补充策略。此外,研究了阻碍大规模采用这些技术的主要挑战,包括与毒性、监管不确定性和经济可行性有关的问题。标准化安全评估和明确规定的管理框架的需要仍然是将实验室研究转化为商业上可行的产品的主要障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emerging trends in nanotechnologies for vitamin delivery: Innovation and future prospects
Nanotechnology has emerged as a cutting-edge approach to improving Vitamin Delivery systems, addressing critical challenges such as poor solubility, instability, and limited bioavailability. Conventional Vitamin Formulations are often challenged with rapid degradation and inefficient absorption, reducing their effectiveness. Integrating nanocarriers - including polymeric nanoparticles, lipid-based nanoparticles, metal-based systems, liposomes, and nano-emulsions - has demonstrated significant potential in enhancing vitamin stability and controlled release, optimizing nutrient uptake in the body. This review explores the diverse applications of nanotechnology in Vitamin Delivery, emphasizing the advantages of various nanocarrier systems. It discusses how nanoscale delivery platforms improve vitamin protection, solubility, and absorption, potentially leading to more effective supplementation strategies. Additionally, key challenges hindering the large-scale adoption of these technologies are examined, including concerns related to toxicity, regulatory uncertainties, and economic feasibility. The need for standardized safety assessments and well-defined regulatory frameworks remains a major hurdle in translating laboratory research into commercially viable products.
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