{"title":"立即预约戒烟诊所：慢性气道疾病戒烟的关键-一项多中心随机研究。","authors":"Dilek Karadoğan, Tahsin Gökhan Telatar, İlknur Kaya, Siahmet Atlı, Neslihan Köse Kabil, Feride Marım, Merve Yumrukuz Şenel, Aycan Yüksel, Burcu Yalçın, Ökkeş Gültekin, Merve Erçelik, Metin Akgün","doi":"10.18332/tid/204254","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>A significant proportion of patients with chronic airway diseases continue to smoke even after the diagnosis. In addition, smoking cessation support continues to be a neglected issue in real-life settings by physicians for that patient group. Therefore, in our search for a solution to this issue, we conducted our study to evaluate the effect of arranging immediate appointments to smoking cessation outpatient clinics on smoking cessation success in patients with chronic airway disease.</p><p><strong>Methods: </strong>This multicenter, randomized, parallel-arm prospective study (NCT05764343) was conducted in pulmonary outpatient clinics between November 2022 and June 2023. Current smoker patients aged ≥18 years diagnosed with COPD, asthma, or bronchiectasis for at least 6 months were included and sequentially randomized in a 1:1 ratio. Both arms received brief smoking cessation interventions, and the intervention arm had immediate access to a smoking cessation clinic appointment. In contrast, the control arm received a standard quitline appointment for routine service. The primary endpoint was the self-reported smoking cessation rate at 3 months, analyzed using an intentionto-treat approach.</p><p><strong>Results: </strong>The study comprised 198 patients in the immediate appointment arm and 199 in the usual care arm. The quit rate was significantly higher in the immediate appointment arm (26.7%) than in the usual care arm (16.5%, p=0.014). Access to smoking cessation medication was 69.3% in the intervention group against 22.0% in the control group (p<0.001). Multivariable analysis identified access to smoking cessation medication as the sole significant predictor of cessation success at 3 months (adjusted odds ratio, AOR=5.64; 95% CI: 2.89-11.03).</p><p><strong>Conclusions: </strong>Our study revealed that access to evidence-based smoking cessation support is positively associated with successful quitting. Compared to the usual care arm, the immediately appointment-scheduled arm has a higher access rate of cessation support. Therefore, smoking cessation support, including pharmacotherapy, should be part of routine care for patients with chronic airway diseases.</p><p><strong>Clinical trial registration: </strong>The study is registered on the official website of ClinicalTrials.gov Identifier: ID NCT05764343.</p>","PeriodicalId":23202,"journal":{"name":"Tobacco Induced Diseases","volume":"23 ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139391/pdf/","citationCount":"0","resultStr":"{\"title\":\"Immediately scheduled for an appointment to smoking cessation clinics: Key to quitting smoking in chronic airway disease - a multicenter randomized study.\",\"authors\":\"Dilek Karadoğan, Tahsin Gökhan Telatar, İlknur Kaya, Siahmet Atlı, Neslihan Köse Kabil, Feride Marım, Merve Yumrukuz Şenel, Aycan Yüksel, Burcu Yalçın, Ökkeş Gültekin, Merve Erçelik, Metin Akgün\",\"doi\":\"10.18332/tid/204254\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>A significant proportion of patients with chronic airway diseases continue to smoke even after the diagnosis. In addition, smoking cessation support continues to be a neglected issue in real-life settings by physicians for that patient group. Therefore, in our search for a solution to this issue, we conducted our study to evaluate the effect of arranging immediate appointments to smoking cessation outpatient clinics on smoking cessation success in patients with chronic airway disease.</p><p><strong>Methods: </strong>This multicenter, randomized, parallel-arm prospective study (NCT05764343) was conducted in pulmonary outpatient clinics between November 2022 and June 2023. Current smoker patients aged ≥18 years diagnosed with COPD, asthma, or bronchiectasis for at least 6 months were included and sequentially randomized in a 1:1 ratio. Both arms received brief smoking cessation interventions, and the intervention arm had immediate access to a smoking cessation clinic appointment. In contrast, the control arm received a standard quitline appointment for routine service. The primary endpoint was the self-reported smoking cessation rate at 3 months, analyzed using an intentionto-treat approach.</p><p><strong>Results: </strong>The study comprised 198 patients in the immediate appointment arm and 199 in the usual care arm. The quit rate was significantly higher in the immediate appointment arm (26.7%) than in the usual care arm (16.5%, p=0.014). Access to smoking cessation medication was 69.3% in the intervention group against 22.0% in the control group (p<0.001). Multivariable analysis identified access to smoking cessation medication as the sole significant predictor of cessation success at 3 months (adjusted odds ratio, AOR=5.64; 95% CI: 2.89-11.03).</p><p><strong>Conclusions: </strong>Our study revealed that access to evidence-based smoking cessation support is positively associated with successful quitting. Compared to the usual care arm, the immediately appointment-scheduled arm has a higher access rate of cessation support. Therefore, smoking cessation support, including pharmacotherapy, should be part of routine care for patients with chronic airway diseases.</p><p><strong>Clinical trial registration: </strong>The study is registered on the official website of ClinicalTrials.gov Identifier: ID NCT05764343.</p>\",\"PeriodicalId\":23202,\"journal\":{\"name\":\"Tobacco Induced Diseases\",\"volume\":\"23 \",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139391/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tobacco Induced Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.18332/tid/204254\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tobacco Induced Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18332/tid/204254","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Immediately scheduled for an appointment to smoking cessation clinics: Key to quitting smoking in chronic airway disease - a multicenter randomized study.
Introduction: A significant proportion of patients with chronic airway diseases continue to smoke even after the diagnosis. In addition, smoking cessation support continues to be a neglected issue in real-life settings by physicians for that patient group. Therefore, in our search for a solution to this issue, we conducted our study to evaluate the effect of arranging immediate appointments to smoking cessation outpatient clinics on smoking cessation success in patients with chronic airway disease.
Methods: This multicenter, randomized, parallel-arm prospective study (NCT05764343) was conducted in pulmonary outpatient clinics between November 2022 and June 2023. Current smoker patients aged ≥18 years diagnosed with COPD, asthma, or bronchiectasis for at least 6 months were included and sequentially randomized in a 1:1 ratio. Both arms received brief smoking cessation interventions, and the intervention arm had immediate access to a smoking cessation clinic appointment. In contrast, the control arm received a standard quitline appointment for routine service. The primary endpoint was the self-reported smoking cessation rate at 3 months, analyzed using an intentionto-treat approach.
Results: The study comprised 198 patients in the immediate appointment arm and 199 in the usual care arm. The quit rate was significantly higher in the immediate appointment arm (26.7%) than in the usual care arm (16.5%, p=0.014). Access to smoking cessation medication was 69.3% in the intervention group against 22.0% in the control group (p<0.001). Multivariable analysis identified access to smoking cessation medication as the sole significant predictor of cessation success at 3 months (adjusted odds ratio, AOR=5.64; 95% CI: 2.89-11.03).
Conclusions: Our study revealed that access to evidence-based smoking cessation support is positively associated with successful quitting. Compared to the usual care arm, the immediately appointment-scheduled arm has a higher access rate of cessation support. Therefore, smoking cessation support, including pharmacotherapy, should be part of routine care for patients with chronic airway diseases.
Clinical trial registration: The study is registered on the official website of ClinicalTrials.gov Identifier: ID NCT05764343.
期刊介绍：
Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community.
The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.
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