Renee Liu, Carlos Cifuentes-González, Sapna Gangaputra, Ikhwanuliman Putera, William Rojas-Carabali, Rina La Distia Nora, Alejandra de-la-Torre, Vishali Gupta, James T Rosenbaum, Rupesh Agrawal
{"title":"视网膜血管炎的诊断和管理实践调查:国际葡萄膜炎研究小组(IUSG)视网膜血管炎研究(修订)-报告5。","authors":"Renee Liu, Carlos Cifuentes-González, Sapna Gangaputra, Ikhwanuliman Putera, William Rojas-Carabali, Rina La Distia Nora, Alejandra de-la-Torre, Vishali Gupta, James T Rosenbaum, Rupesh Agrawal","doi":"10.1080/09273948.2025.2503337","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Retinal vasculitis (RV) is a complex inflammatory disorder of retinal blood vessels with variability in diagnosis, classification, and management. Despite efforts to standardize definitions, discrepancies persist regarding clinical features, systemic associations, and treatment approaches. This study aimed to assess clinical practices among uveitis specialists to identify areas requiring consensus.</p><p><strong>Methods: </strong>A cross-sectional, semi-structured survey was conducted among members of the International Uveitis Study Group (IUSG). Eligible participants were uveitis specialists with formal training in ocular inflammation. The survey included 120 questions on diagnosis, imaging, systemic associations, and management strategies. Responses were collected anonymously via REDCap (January to August 2024).</p><p><strong>Results: </strong>Fifty-five specialists participated, mainly from Europe, Asia, and North America. Most rated their RV knowledge as \"adequate\" or \"proficient.\" While 85.5% agreed on a definition involving retinal vascular abnormalities with intraocular inflammation, variability persisted in diagnostic and management practices. Diagnostic testing prioritized infectious and systemic causes. Wide-field imaging and fluorescein angiography were commonly used. Methotrexate, mycophenolate, and adalimumab were preferred treatments. Treatment success was primarily defined by improvements in vascular leakage and macular edema. Monitoring practices and referral patterns varied.</p><p><strong>Conclusion: </strong>Substantial variability exists in RV diagnosis and management, highlighting the need for standardized clinical guidelines.</p>","PeriodicalId":19406,"journal":{"name":"Ocular Immunology and Inflammation","volume":" ","pages":"1-9"},"PeriodicalIF":2.6000,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Survey of Diagnostic and Management Practices in Retinal Vasculitis: International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe)-Report 5.\",\"authors\":\"Renee Liu, Carlos Cifuentes-González, Sapna Gangaputra, Ikhwanuliman Putera, William Rojas-Carabali, Rina La Distia Nora, Alejandra de-la-Torre, Vishali Gupta, James T Rosenbaum, Rupesh Agrawal\",\"doi\":\"10.1080/09273948.2025.2503337\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Retinal vasculitis (RV) is a complex inflammatory disorder of retinal blood vessels with variability in diagnosis, classification, and management. Despite efforts to standardize definitions, discrepancies persist regarding clinical features, systemic associations, and treatment approaches. This study aimed to assess clinical practices among uveitis specialists to identify areas requiring consensus.</p><p><strong>Methods: </strong>A cross-sectional, semi-structured survey was conducted among members of the International Uveitis Study Group (IUSG). Eligible participants were uveitis specialists with formal training in ocular inflammation. The survey included 120 questions on diagnosis, imaging, systemic associations, and management strategies. Responses were collected anonymously via REDCap (January to August 2024).</p><p><strong>Results: </strong>Fifty-five specialists participated, mainly from Europe, Asia, and North America. Most rated their RV knowledge as \\\"adequate\\\" or \\\"proficient.\\\" While 85.5% agreed on a definition involving retinal vascular abnormalities with intraocular inflammation, variability persisted in diagnostic and management practices. Diagnostic testing prioritized infectious and systemic causes. Wide-field imaging and fluorescein angiography were commonly used. Methotrexate, mycophenolate, and adalimumab were preferred treatments. Treatment success was primarily defined by improvements in vascular leakage and macular edema. Monitoring practices and referral patterns varied.</p><p><strong>Conclusion: </strong>Substantial variability exists in RV diagnosis and management, highlighting the need for standardized clinical guidelines.</p>\",\"PeriodicalId\":19406,\"journal\":{\"name\":\"Ocular Immunology and Inflammation\",\"volume\":\" \",\"pages\":\"1-9\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ocular Immunology and Inflammation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09273948.2025.2503337\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ocular Immunology and Inflammation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09273948.2025.2503337","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
A Survey of Diagnostic and Management Practices in Retinal Vasculitis: International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe)-Report 5.
Purpose: Retinal vasculitis (RV) is a complex inflammatory disorder of retinal blood vessels with variability in diagnosis, classification, and management. Despite efforts to standardize definitions, discrepancies persist regarding clinical features, systemic associations, and treatment approaches. This study aimed to assess clinical practices among uveitis specialists to identify areas requiring consensus.
Methods: A cross-sectional, semi-structured survey was conducted among members of the International Uveitis Study Group (IUSG). Eligible participants were uveitis specialists with formal training in ocular inflammation. The survey included 120 questions on diagnosis, imaging, systemic associations, and management strategies. Responses were collected anonymously via REDCap (January to August 2024).
Results: Fifty-five specialists participated, mainly from Europe, Asia, and North America. Most rated their RV knowledge as "adequate" or "proficient." While 85.5% agreed on a definition involving retinal vascular abnormalities with intraocular inflammation, variability persisted in diagnostic and management practices. Diagnostic testing prioritized infectious and systemic causes. Wide-field imaging and fluorescein angiography were commonly used. Methotrexate, mycophenolate, and adalimumab were preferred treatments. Treatment success was primarily defined by improvements in vascular leakage and macular edema. Monitoring practices and referral patterns varied.
Conclusion: Substantial variability exists in RV diagnosis and management, highlighting the need for standardized clinical guidelines.
期刊介绍:
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.