Molecular dynamics – Driven innovation in lateral flow immunoassay technology: Principles, methods, and applications

Lateral flow immunoassay (LFIA), a widely used point - of - care testing tool, holds significant value in disease diagnosis, food safety detection, and environmental monitoring. However, conventional LFIA faces limitations in sensitivity and specificity. This article delves into the application of molecular dynamics in LFIA technology, elaborating on the principles, methods, and applications of molecular dynamics - driven LFIA innovation. It first introduces the basic principles and simulation methods of molecular dynamics. Then, it conducts a detailed analysis of the key roles of molecular dynamics in optimizing LFIA technology, including the simulation of antigen - antibody interactions, optimization of labeling materials, and optimization of detection conditions. Finally, it explores the application prospects of molecular dynamics - driven LFIA technology in disease diagnosis, food safety detection, and environmental monitoring. This article aims to provide a theoretical basis and practical guidance for the further development of LFIA technology, promoting its application in more fields.