68Ga-FAPI-04 PET/CT与18F-FDG PET/CT在转移性副神经节瘤分期中的比较：1例报告。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-11-01 Epub Date: 2025-06-05 DOI:10.1097/RLU.0000000000006007

Yang Liu, Xinfeng Lin, Nina Zhou, Yan Cui, Nan Li

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引用次数: 0

摘要

一名26岁男子偶然发现腹膜后有肿块。18F-FDG PET/CT显示腹膜后肿块、淋巴结和骨病变有强烈摄取。增强MRI显示腹膜后肿块、淋巴结和L5椎体病变明显且类似强化，支持转移诊断。相比之下，68Ga-FAPI-04 PET/CT显示腹膜后肿块强烈摄取，但L5椎体仅轻度摄取，其他病变可忽略。组织病理学检查证实为副神经节瘤。本病例提示68Ga-FAPI-04 PET/CT对转移性副神经节瘤的分期可能不如18F-FDG PET/CT有效。

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Deficiency of 68 Ga-FAPI-04 PET/CT Compared With 18 F-FDG PET/CT in Staging Metastatic Paraganglioma: A Case Report.

A 26-year-old man was incidentally found to have a retroperitoneal mass. 18 F-FDG PET/CT showed intense uptake in the retroperitoneal mass, lymph nodes, and bone lesions. Contrast-enhanced MRI revealed significant and similar enhancement in the retroperitoneal mass, lymph nodes, and the lesion in the L5 vertebral body, supporting the diagnosis of metastases. In contrast, 68 Ga-FAPI-04 PET/CT demonstrated intense uptake in the retroperitoneal mass, but only mild uptake in the L5 vertebral body and negligible uptake in other lesions. Histopathological examination confirmed paraganglioma. This case suggests that 68 Ga-FAPI-04 PET/CT may be less effective than 18 F-FDG PET/CT for staging metastatic paraganglioma.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.