腹腔疾病相关的小肠腺癌和t细胞淋巴瘤的不同生存结局

IF 8 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

American Journal of Gastroenterology Pub Date : 2025-06-05 DOI:10.14309/ajg.0000000000003574

Giovanni Santacroce, Alessandro Vanoli, Nicola Aronico, Paola Ilaria Bianchi, Marco Vincenzo Lenti, Carolina Ciacci, Fabiana Zingone, Umberto Volta, Antonio Calabrò, Luca Elli, Rachele Ciccocioppo, Gino Roberto Corazza, Marco Lucioni, Marco Paulli, Antonio Di Sabatino

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引用次数: 0

摘要

小肠腺癌（SBA）和t细胞淋巴瘤（TCL）是与乳糜泻（CD）相关的罕见但侵袭性的恶性肿瘤。方法：我们回顾性比较了国际转诊中心43例cd相关的SBA和43例cd相关的TCL。讨论：我们的研究结果表明，与cd相关的SBA相比，cd相关的TCL的预后更差。

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Different survival outcomes of small bowel adenocarcinomas and T-cell lymphomas associated to celiac disease.

Introduction: Small bowel adenocarcinoma (SBA) and T-cell lymphoma (TCL) are rare but aggressive malignancies associated with celiac disease (CD).

Methods: We retrospectively compared 43 CD-associated SBA and 43 CD-associated TCL across international referral centers.

Results: CD-associated SBA showed a significantly (p<0.01) better survival than CD-associated TCL. TCL more frequently presented with multifocal involvement and advanced stage, whereas SBA predominantly involved the jejunum. Refractoriness to a gluten-free diet was identified in 70% of TCL, but only in one SBA.

Discussion: Our findings demonstrated a worse prognosis of CD-associated TCL in comparison to CD-associated SBA.

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来源期刊

American Journal of Gastroenterology 医学-胃肠肝病学

CiteScore

11.40

自引率

5.10%

发文量

458

审稿时长

12 months

期刊介绍： Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.