{"title":"生物材料在脑部疾病中的机遇与挑战。","authors":"Wenming Zheng, Mingxia Jiang, Nuo Dong, Huapan Fang, Huayu Tian, Xuesi Chen","doi":"10.1002/adhm.202500746","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, biomaterials have made rapid progress in the application of brain diseases. This review critically examines the latest progress of biomaterials for the diagnosis, treatment, and monitoring of brain diseases, highlighting their potential to revolutionize therapeutic strategies. The multifaceted roles of biomaterials in neural repair, drug delivery to the brain, the diagnosis, and monitoring of brain diseases are discussed in this review. However, the clinical translation of these biomaterials faces numerous challenges. This review provides a comprehensive overview of various brain diseases, conventional treatment methods, and the design principles of biomaterials tailored for this field. This review summarizes the current state of clinical research and outlines the current challenges and future directions of biomaterials in brain diseases. This review also underscores the importance of interdisciplinary collaboration and continuous innovation to overcome existing barriers and fully realize the potential of biomaterials in brain disease management.</p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":" ","pages":"e2500746"},"PeriodicalIF":10.0000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Opportunities and Challenges of Biomaterials in Brain Disease.\",\"authors\":\"Wenming Zheng, Mingxia Jiang, Nuo Dong, Huapan Fang, Huayu Tian, Xuesi Chen\",\"doi\":\"10.1002/adhm.202500746\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In recent years, biomaterials have made rapid progress in the application of brain diseases. This review critically examines the latest progress of biomaterials for the diagnosis, treatment, and monitoring of brain diseases, highlighting their potential to revolutionize therapeutic strategies. The multifaceted roles of biomaterials in neural repair, drug delivery to the brain, the diagnosis, and monitoring of brain diseases are discussed in this review. However, the clinical translation of these biomaterials faces numerous challenges. This review provides a comprehensive overview of various brain diseases, conventional treatment methods, and the design principles of biomaterials tailored for this field. This review summarizes the current state of clinical research and outlines the current challenges and future directions of biomaterials in brain diseases. This review also underscores the importance of interdisciplinary collaboration and continuous innovation to overcome existing barriers and fully realize the potential of biomaterials in brain disease management.</p>\",\"PeriodicalId\":113,\"journal\":{\"name\":\"Advanced Healthcare Materials\",\"volume\":\" \",\"pages\":\"e2500746\"},\"PeriodicalIF\":10.0000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Healthcare Materials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1002/adhm.202500746\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Healthcare Materials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/adhm.202500746","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Opportunities and Challenges of Biomaterials in Brain Disease.
In recent years, biomaterials have made rapid progress in the application of brain diseases. This review critically examines the latest progress of biomaterials for the diagnosis, treatment, and monitoring of brain diseases, highlighting their potential to revolutionize therapeutic strategies. The multifaceted roles of biomaterials in neural repair, drug delivery to the brain, the diagnosis, and monitoring of brain diseases are discussed in this review. However, the clinical translation of these biomaterials faces numerous challenges. This review provides a comprehensive overview of various brain diseases, conventional treatment methods, and the design principles of biomaterials tailored for this field. This review summarizes the current state of clinical research and outlines the current challenges and future directions of biomaterials in brain diseases. This review also underscores the importance of interdisciplinary collaboration and continuous innovation to overcome existing barriers and fully realize the potential of biomaterials in brain disease management.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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