Frontispiece: Self-Optimized Reconstruction of Metal–Organic Frameworks Introduces Cation Vacancies for Selective Electrosynthesis of Hydrogen Peroxide

In their Research Article (e202501930), Guohua Zhao and co-workers report a novel strategy utilizing the self-optimizing restructuring behavior of MOFs to construct cation vacancies, which effectively suppresses excessive O─O bond cleavage during oxygen activation. This strategy promotes the 2e⁻ pathway for H₂O₂ production (right) over the 4e⁻ pathway generating H₂O (left). By employing a solid-state electrolyte cell, direct synthesis of ultrahigh-concentration H₂O₂ aqueous solution (>8 wt%) is achieved.