天然产物化学作为药学教育的重要课题：情境分析与建议

IF 1.3 Q3 EDUCATION, SCIENTIFIC DISCIPLINES

Currents in Pharmacy Teaching and Learning Pub Date : 2025-06-07 DOI:10.1016/j.cptl.2025.102410

Ahmed Ashour , Mohamed Mirghani , Mona Mohamed , Wadah Osman , Mohammed Hamed Alqarni , Ahmed I. Foudah , Ahmed A. Zaki , Reham M. Samra

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引用次数: 0

摘要

药学实践产生的基础学科通常被认为是生药学。这一领域可以被定义为药用植物及其衍生物的研究，反映了药物使用的历史演变，从粗草药的配方过渡到药物发现领域中活性药物化合物的复杂分离和表征。没有一门科学学科是一成不变的，生药学的现代和全面定义包括对生物源或天然衍生药物以及自然产生的毒物的分析。高效液相色谱（HPLC）、核磁共振（NMR）、质谱等植物化学分析技术的快速发展，极大地提高了我们鉴定和定量生物活性化合物的能力，使生药学研究变得非常丰富和有趣。生药学面临着诸多挑战。目的对中东、阿拉伯地区和非洲一些非阿拉伯国家的药学院开设生药学课程的现状进行综述；并评价其伴随全球对植物化学和天然产物生物活性的日益关注。方法从网站获取所有阿拉伯、中东国家和非洲地区前10名的非阿拉伯大学名单。各国排名前十的大学来自（www.edurank.org）。每所大学通过其官方网站单独搜索是否包含药学院，如果该大学没有药学院，则被排除在研究之外。然后，通过选定的药学院的官方网站获取我们研究所需的信息。结果共评估了22个中东和阿拉伯国家，包括80所大学。只有43个学院（53.75%）设有独立的生药学部门。在66个院系中，29个（43.9%）院系修读应用生药学课程，而37个（56.1%）院系没有修读任何高级课程。在66个学院中，28个（42.4%）在其课程中包括植物疗法课程，而38个（57.6%）没有。在非阿拉伯非洲国家，10个学院中有7个（70%）设有生药学系；只有1人（10%）缺乏相关课程。此外，8个学院（80%）涵盖应用生药学主题，9个学院（90%）研究植物疗法或相关学科。结论在考虑生药学（经典生药学）的历史基础和现代领域的进步的同时，有必要解决这些新的要求。第二世界和发展中国家的大学可以加强它们在生药学方面的研究，这可以提高它们在国际机构中的评级和排名。

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Natural product chemistry as an important topic in pharmacy education: Situational analysis and recommendations

Background

The foundational discipline from which the practice of Pharmacy has emerged is commonly recognized as Pharmacognosy. This field can be defined as the study of medicinal plants and their derivatives, reflecting the historical evolution of drug use, which has transitioned from the formulation of crude herbal remedies to the sophisticated isolation and characterization of active pharmaceutical compounds in the realm of drug discovery. No scientific subject remains static and a modern and comprehensive definition of Pharmacognosy includes the analysis of biogenic or naturally derived pharmaceuticals, as well as naturally occurring poisons. Rapid advancements of analytical techniques in phytochemistry, such as high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry, which have greatly enhanced our ability to identify and quantify bioactive compounds and made Pharmacognostical research very informative and interesting. Pharmacognosy is confronted with many challenges.

Objectives

The objective of this review is to assess the current situation of Pharmacognosy, as a subject, in the curriculums in some colleges of Pharmacy in Middle East, Arab region and some non-Arab African countries; and to evaluate its accompaniment with the global increase focus in phytochemistry and biological activities in natural products.

Methods

A list of all Arab, Middle East countries and top ten non-Arab African universities was obtained from the website. The top 10 universities of each country were obtained from (www.edurank.org). Each university was individually searched if it contains a faculty of Pharmacy or not through its official website, if the university has no faculty of Pharmacy it was excluded from the study. Then, the official websites of the selected faculties of Pharmacy were used to obtain the needed information of our study.

Results

A total of 22 Middle East and Arab countries were assessed, including 80 universities. Only 43 faculties (53.75 %) have a separate Pharmacognosy department. Of the 66 faculties, 29 (43.9 %) study courses in applied Pharmacognosy, while 37 (56.1 %) do not study any advanced topics in their curriculum. Out of 66 faculties, 28 (42.4 %) include Phytotherapy courses in their curriculum, while 38 (57.6 %) do not. In non-Arab African countries, 7 out of 10 faculties (70 %) have a Pharmacognosy department; only 1 (10 %) lacks relevant courses. Additionally, 8 faculties (80 %) cover applied Pharmacognosy topics, and 9 faculties (90 %) study Phytotherapy or related subjects.

Conclusion

It is essential to address these new requirements while considering the historical foundations of Pharmacognosy (classical Pharmacognosy) alongside modern advancements in the field. Universities in second world and developing countries could enhance their research in Pharmacognosy, which could improve their ratings and rankings among international institutions.

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来源期刊

Currents in Pharmacy Teaching and Learning EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

2.10

自引率

16.70%

发文量

192