康复社区研究：支持社区干预以减少阿片类药物过量死亡的数据措施

IF 3.9 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2025-06-02 DOI:10.1016/j.drugalcdep.2025.112738

Svetla Slavova , Jennifer Villani , Daniel J. Feaster , Austin Booth , JaNae L. Holloway , Peter J. Rock , Lindsey R. Hammerslag , Aimee Mack , Charles E. Knott , John V. McCarthy , Jeffery Talbert , Marc R. LaRochelle , Bridget Freisthler , Brent J. Gibbons , Gregory Patts , Matthew J. Bullard , Sharon L. Walsh

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引用次数: 0

摘要

康复社区研究（HCS）在肯塔基州、马萨诸塞州、纽约州和俄亥俄州的67个社区测试了一项基于社区的干预措施，以减少阿片类药物过量死亡。本文介绍了HCS监测干预的措施，报告了基准的粗略比率，并强调了在国家政策背景下解释司法趋势的重要性。方法提出HCS测量方法的技术规范和常用数据模型。评估期（2021年7月至2022年6月）的原油价格由州和研究机构（干预/第一波或等待上市/第二波社区）报告，以及2017年至2023年的纵向趋势。2023年是第一波社区的干预后时期，是第二波社区的干预年。结果经过2020-2021年的空前增长，HCS粗阿片类药物过量死亡率在2023年有所下降，但仍高于2019年大流行前的死亡率。在一些州，非西班牙裔黑人的阿片类药物过量死亡率超过100/100,000。为了应对肯塔基州阿片类药物过量死亡人数的迅速增加，HCS团队扩大了肯塔基州干预社区的纳洛酮分布，在2021年第三季度增加了10倍（1498.2单位/10万居民）。在评估期间，马萨诸塞州干预社区的美沙酮治疗阿片类药物使用障碍（mod）治疗率最高（274/1000），而肯塔基州的丁丙诺啡mod治疗率最高（441/1000）。结论HCS措施支持人群层面阿片类药物过量预防干预措施和政策的综合规划和评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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HEALing Communities Study: Data measures for supporting a community-based intervention to reduce opioid overdose deaths

Introduction

The HEALing Communities Study (HCS) tested a community-based intervention in 67 communities across Kentucky, Massachusetts, New York, and Ohio to reduce opioid overdose deaths. This paper introduces the HCS measures for monitoring the intervention uptake, reports crude rates for benchmarking, and highlights the importance of interpreting jurisdictional trends in the context of state policies.

Methods

We present technical specifications for the HCS measures and the common data model. Crude rates for the evaluation period (July 2021- June 2022) are reported by state and study arm (intervention/Wave 1 or wait-listed/Wave 2 communities), along with longitudinal trends from 2017 to 2023. Year 2023 serves as a post-intervention period for Wave 1 communities and an intervention year for Wave 2 communities.

Results

After unprecedented increases in 2020–2021, the HCS crude opioid overdose death rates declined in 2023, but remained higher than the 2019 pre-pandemic rates. Opioid overdose death rates exceeded 100/100,000 adults among Non-Hispanic Black individuals in several states. In response to the rapid increase in opioid overdose deaths in Kentucky, the HCS team expanded the naloxone distribution in Kentucky intervention communities, reaching a 10-fold increase in Quarter 3 of 2021 (1498.2 units/100,000 residents). The methadone medication for opioid use disorder (MOUD) treatment rate for Medicaid enrollees with opioid use disorder during the evaluation period was highest in Massachusetts intervention communities (274/1000), while the buprenorphine MOUD treatment rate was highest in Kentucky (441/1000).

Conclusions

The HCS measures support comprehensive planning and evaluation of population-level opioid overdose prevention interventions and policies.

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.