Dínimo Bolivar-Saénz , Nohora Patricia Bonilla Solano , Georgina González Tarazona , José Antonio Villamizar Silva , Yohana Alfonso Guerra , Juan Camilo Arango Brand , Andrea Torres Contreras
{"title":"经临床表现、影像学及内窥镜诊断的肠结核合并肺结核:1例报告及文献综述","authors":"Dínimo Bolivar-Saénz , Nohora Patricia Bonilla Solano , Georgina González Tarazona , José Antonio Villamizar Silva , Yohana Alfonso Guerra , Juan Camilo Arango Brand , Andrea Torres Contreras","doi":"10.1016/j.clinmicnews.2025.05.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Intestinal tuberculosis (ITB) represents an atypical clinical manifestation of tuberculosis, constituting a significant proportion of extrapulmonary cases. This study, combining a case report and a narrative literature review, aims to deepen the understanding of ITB and its clinical characteristics.</div></div><div><h3>Case presentation</h3><div>We present a clinical case of a young patient with concomitant pulmonary tuberculosis and chronic gastrointestinal symptoms. Imaging studies revealed intestinal wall thickening in the ileum and cecum, findings corroborated by colonoscopy, which showed multiple ulcers and an inflammatory response on biopsy, albeit without direct identification of the bacillus. The patient responded favorably to standard anti-tuberculosis treatment.</div></div><div><h3>Discussion</h3><div>Our findings, coupled with the literature review, suggest that ITB can present with nonspecific clinical features, hindering early diagnosis. Coexistence with pulmonary tuberculosis is common, and complications such as intestinal obstruction may necessitate surgical intervention.</div></div><div><h3>Conclusion</h3><div>Intestinal tuberculosis poses a diagnostic challenge due to the variability of its clinical manifestations and the lack of specific diagnostic tests. A high index of clinical suspicion, particularly in patients with pulmonary tuberculosis or risk factors, is crucial for early diagnosis, appropriate management, and consequently enhance the prognosis of the disease.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"52 ","pages":"Pages 4-9"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intestinal tuberculosis diagnosed by clinical presentation, imaging, and endoscopy, associated with pulmonary tuberculosis: A case report and narrative literature review\",\"authors\":\"Dínimo Bolivar-Saénz , Nohora Patricia Bonilla Solano , Georgina González Tarazona , José Antonio Villamizar Silva , Yohana Alfonso Guerra , Juan Camilo Arango Brand , Andrea Torres Contreras\",\"doi\":\"10.1016/j.clinmicnews.2025.05.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>Intestinal tuberculosis (ITB) represents an atypical clinical manifestation of tuberculosis, constituting a significant proportion of extrapulmonary cases. This study, combining a case report and a narrative literature review, aims to deepen the understanding of ITB and its clinical characteristics.</div></div><div><h3>Case presentation</h3><div>We present a clinical case of a young patient with concomitant pulmonary tuberculosis and chronic gastrointestinal symptoms. Imaging studies revealed intestinal wall thickening in the ileum and cecum, findings corroborated by colonoscopy, which showed multiple ulcers and an inflammatory response on biopsy, albeit without direct identification of the bacillus. The patient responded favorably to standard anti-tuberculosis treatment.</div></div><div><h3>Discussion</h3><div>Our findings, coupled with the literature review, suggest that ITB can present with nonspecific clinical features, hindering early diagnosis. Coexistence with pulmonary tuberculosis is common, and complications such as intestinal obstruction may necessitate surgical intervention.</div></div><div><h3>Conclusion</h3><div>Intestinal tuberculosis poses a diagnostic challenge due to the variability of its clinical manifestations and the lack of specific diagnostic tests. A high index of clinical suspicion, particularly in patients with pulmonary tuberculosis or risk factors, is crucial for early diagnosis, appropriate management, and consequently enhance the prognosis of the disease.</div></div>\",\"PeriodicalId\":39211,\"journal\":{\"name\":\"Clinical Microbiology Newsletter\",\"volume\":\"52 \",\"pages\":\"Pages 4-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Microbiology Newsletter\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0196439925000200\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Microbiology Newsletter","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0196439925000200","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Intestinal tuberculosis diagnosed by clinical presentation, imaging, and endoscopy, associated with pulmonary tuberculosis: A case report and narrative literature review
Objective
Intestinal tuberculosis (ITB) represents an atypical clinical manifestation of tuberculosis, constituting a significant proportion of extrapulmonary cases. This study, combining a case report and a narrative literature review, aims to deepen the understanding of ITB and its clinical characteristics.
Case presentation
We present a clinical case of a young patient with concomitant pulmonary tuberculosis and chronic gastrointestinal symptoms. Imaging studies revealed intestinal wall thickening in the ileum and cecum, findings corroborated by colonoscopy, which showed multiple ulcers and an inflammatory response on biopsy, albeit without direct identification of the bacillus. The patient responded favorably to standard anti-tuberculosis treatment.
Discussion
Our findings, coupled with the literature review, suggest that ITB can present with nonspecific clinical features, hindering early diagnosis. Coexistence with pulmonary tuberculosis is common, and complications such as intestinal obstruction may necessitate surgical intervention.
Conclusion
Intestinal tuberculosis poses a diagnostic challenge due to the variability of its clinical manifestations and the lack of specific diagnostic tests. A high index of clinical suspicion, particularly in patients with pulmonary tuberculosis or risk factors, is crucial for early diagnosis, appropriate management, and consequently enhance the prognosis of the disease.
期刊介绍:
Highly respected for its ability to keep pace with advances in this fast moving field, Clinical Microbiology Newsletter has quickly become a “benchmark” for anyone in the lab. Twice a month the newsletter reports on changes that affect your work, ranging from articles on new diagnostic techniques, to surveys of how readers handle blood cultures, to editorials questioning common procedures and suggesting new ones.