住院印度老年人潜在不适当用药的多标准评估：比较Beers、STOPP和FORTA。

IF 2.2 3区医学 Q2 GERONTOLOGY

Journal of Applied Gerontology Pub Date : 2025-06-05 DOI:10.1177/07334648251348704

Jehath Syed, Prathiba Pereira, C J Tejeswini, Shilpa Avarebeel, Kshama Ramesh, Madhan Ramesh, Krishna Undela, Sri Harsha Chalasani

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引用次数: 0

摘要

本研究使用三个标准（Beers 2019、STOPP v2和FORTA 2021）比较了印度南部住院老年人的潜在不适当药物（PIMs）。在这项597例患者（平均年龄：72.80±7.41岁）的横断面研究中，PIM的患病率在所有标准中都非常高：Beers (99.33%)， STOPP（99.16%）和FORTA（99.83%）。每位患者的平均pim分别为：Beers（3.89±1.84）、STOPP（3.77±1.92）和FORTA（7.94±3.22）。Cohen's kappa显示Beers和STOPP标准之间的一致性（κ = 0.252, p < 0.001），但与FORTA的一致性较差。Bland-Altman分析表明，每种工具与标准化PIM平均值之间的一致性是可以接受的。在Beers （OR = 2.504, p = 0.008）和STOPP标准（OR = 1.685, p = 0.008）中，住院期间用药次数是PIM使用的唯一显著预测因子。结果表明需要进行系统的药物评价。

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Multi-Criteria Assessment of Potentially Inappropriate Medications in Hospitalized Indian Older Adults: Comparing Beers, STOPP, and FORTA.

This study compared potentially inappropriate medications (PIMs) using three criteria (Beers 2019, STOPP v2, and FORTA 2021) in hospitalized older adults in Southern India. In this cross-sectional study of 597 patients (mean age: 72.80 ± 7.41 years), PIM prevalence was remarkably high across all criteria: Beers (99.33%), STOPP (99.16%), and FORTA (99.83%). The mean PIMs per patient were: Beers (3.89 ± 1.84), STOPP (3.77 ± 1.92), and FORTA (7.94 ± 3.22). Cohen's kappa showed fair agreement between Beers and STOPP criteria (κ = 0.252, p < .001), but poor agreement with FORTA. Bland-Altman analysis indicated acceptable agreement between each tool and mean standardized PIM value. The number of medications during hospitalization was the only significant predictor of PIM use in both Beers (OR = 2.504, p = .008) and STOPP criteria (OR = 1.685, p = .008). Results highlight the need for systematic medication review.

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来源期刊

Journal of Applied Gerontology GERONTOLOGY-

CiteScore

5.10

自引率

13.30%

发文量

202

期刊介绍： The Journal of Applied Gerontology (JAG) is the official journal of the Southern Gerontological Society. It features articles that focus on research applications intended to improve the quality of life of older persons or to enhance our understanding of age-related issues that will eventually lead to such outcomes. We construe application broadly and encourage contributions across a range of applications toward those foci, including interventions, methodology, policy, and theory. Manuscripts from all disciplines represented in gerontology are welcome. Because the circulation and intended audience of JAG is global, contributions from international authors are encouraged.