待售的新基因：双病毒基因组中额外的开放阅读框。

IF 14 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in Microbiology Pub Date : 2025-05-30 DOI:10.1016/j.tim.2025.05.003

Huang Tan, Fangfang Li, Xueping Zhou, Rosa Lozano-Durán

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引用次数: 0

摘要

在它们的DNA基因组中，毁灭性的植物感染双病毒含有部分重叠的基因，这些基因编码多功能蛋白质。几十年来，双病毒基因组被认为包含4到8个开放阅读框架（orf）；现在，一系列独立研究发现了额外orf存在的证据，揭示了它们的编码空间仍有待充分探索。

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New genes on the block: additional open reading frames in the genomes of geminiviruses.

In their DNA genomes, the devastating plant-infecting geminiviruses contain partially overlapping genes which encode multifunctional proteins. For decades, geminiviral genomes were believed to contain four to eight open-reading frames (ORFs); now, a burst of independent works has found evidence for the existence of additional ORFs, revealing that their coding space remains to be fully explored.

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来源期刊

Trends in Microbiology 生物-生化与分子生物学

CiteScore

25.30

自引率

0.60%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.