天然腙衍生物：来源、结构和生物活性。

IF 3.3 3区医学 Q2 CHEMISTRY, MEDICINAL

Mini reviews in medicinal chemistry Pub Date : 2025-06-04 DOI:10.2174/0113895575390008250520114953

Hagar Mohamed Mohamed, Hazem G A Hussein, Gamal A Mohamed, Shaimaa G A Mohamed, Sabrin R M Ibrahim

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引用次数: 0

摘要

含腙类化合物是一类生物活性化合物，以其独特的化学特征和多样的生物活性而闻名。天然腙衍生物已从各种天然来源中鉴定出来，包括细菌、植物、真菌和海洋生物。本文对1967年至2025年3月间发表的关于天然腙衍生物的来源、结构特征和生物活性的研究进行了综述。本论文共综述了72个化合物，引用文献75篇。在这项工作中报告的发现突出了这些化合物在药物研究和药物发现中的治疗潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Natural Hydrazone Derivatives: Their Sources, Structures, and Bioactivities.

Hydrazone-containing compounds are a diverse group of bioactive compounds known for their unique chemical features and diverse biological activities. Natural hydrazone derivatives have been identified from various natural sources, including bacteria, plants, fungi, and marine organisms. This work provides a comprehensive review of published works on natural hydrazone derivatives, including their sources, structural features, and biological activity in the period from 1967 to March 2025. In this work, 72 compounds were reviewed, along with 75 references being cited. The reported findings in this work highlight the therapeutic potential of these compounds in pharmaceutical research and drug discovery.

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来源期刊

Mini reviews in medicinal chemistry 医学-医药化学

CiteScore

7.80

自引率

0.00%

发文量

231

审稿时长

6 months

期刊介绍： The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines. Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.