{"title":"用于儿童癌症早期检测的纳米光学(生物)传感平台。","authors":"Chou-Yi Hsu, Anjan Kumar, Prakash Kanjariya, Asha Rajiv, Aditya Kashyap, Helen Merina Albert, Sumit Pokhriyal, Rajashree Panigrahi","doi":"10.1007/s00604-025-07246-2","DOIUrl":null,"url":null,"abstract":"<p><p>Pediatric cancer refers to cancers that occur in children and adolescents, typically defined as those occuring under the age of 18. Although childhood cancers are relatively rare compared to adult cancers, they are a leading cause of death by disease in children. Early detection of childhood cancer is crucial for improving treatment outcomes and survival rates. To detect pediatric cancers in their early stages, the identification of biomarkers can be very helpful. Optical sensors and biosensors, as new analytical devices, can be used as a powerful and non-invasive tool to detect and quantify various cancer-specific biomarkers. Nanomaterials play a transformative role in the development of optical (bio)sensors, enhancing their sensitivity, specificity, and overall performance. Nano optical (bio)sensors provide a non-invasive, swift, and cost-effective method for the early detection of pediatric cancer by identifying cancer-related biomarkers.</p>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 7","pages":"406"},"PeriodicalIF":5.3000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nano optical (bio)sensing platforms for early detection of pediatric cancer.\",\"authors\":\"Chou-Yi Hsu, Anjan Kumar, Prakash Kanjariya, Asha Rajiv, Aditya Kashyap, Helen Merina Albert, Sumit Pokhriyal, Rajashree Panigrahi\",\"doi\":\"10.1007/s00604-025-07246-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Pediatric cancer refers to cancers that occur in children and adolescents, typically defined as those occuring under the age of 18. Although childhood cancers are relatively rare compared to adult cancers, they are a leading cause of death by disease in children. Early detection of childhood cancer is crucial for improving treatment outcomes and survival rates. To detect pediatric cancers in their early stages, the identification of biomarkers can be very helpful. Optical sensors and biosensors, as new analytical devices, can be used as a powerful and non-invasive tool to detect and quantify various cancer-specific biomarkers. Nanomaterials play a transformative role in the development of optical (bio)sensors, enhancing their sensitivity, specificity, and overall performance. Nano optical (bio)sensors provide a non-invasive, swift, and cost-effective method for the early detection of pediatric cancer by identifying cancer-related biomarkers.</p>\",\"PeriodicalId\":705,\"journal\":{\"name\":\"Microchimica Acta\",\"volume\":\"192 7\",\"pages\":\"406\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microchimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s00604-025-07246-2\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s00604-025-07246-2","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Nano optical (bio)sensing platforms for early detection of pediatric cancer.
Pediatric cancer refers to cancers that occur in children and adolescents, typically defined as those occuring under the age of 18. Although childhood cancers are relatively rare compared to adult cancers, they are a leading cause of death by disease in children. Early detection of childhood cancer is crucial for improving treatment outcomes and survival rates. To detect pediatric cancers in their early stages, the identification of biomarkers can be very helpful. Optical sensors and biosensors, as new analytical devices, can be used as a powerful and non-invasive tool to detect and quantify various cancer-specific biomarkers. Nanomaterials play a transformative role in the development of optical (bio)sensors, enhancing their sensitivity, specificity, and overall performance. Nano optical (bio)sensors provide a non-invasive, swift, and cost-effective method for the early detection of pediatric cancer by identifying cancer-related biomarkers.
期刊介绍:
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.