M.Z. Nazario-Pérez , A.P. Quiles-Méndez , I. Pastrana-Echevarría , R. Brito -Sánchez , G. Ruiz-Deyá
{"title":"阴囊外蕈样肿块:一例年轻成人临床T4睾丸癌","authors":"M.Z. Nazario-Pérez , A.P. Quiles-Méndez , I. Pastrana-Echevarría , R. Brito -Sánchez , G. Ruiz-Deyá","doi":"10.1016/j.eucr.2025.103091","DOIUrl":null,"url":null,"abstract":"<div><div>Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk sac tumor. Despite guideline-directed systemic chemotherapy, the course was complicated by tumor-related bleeding and venous thromboembolism, resulting in death from massive pulmonary embolism. This case highlights the aggressiveness of adult yolk sac tumors and need for early intervention.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"61 ","pages":"Article 103091"},"PeriodicalIF":0.5000,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult\",\"authors\":\"M.Z. Nazario-Pérez , A.P. Quiles-Méndez , I. Pastrana-Echevarría , R. Brito -Sánchez , G. Ruiz-Deyá\",\"doi\":\"10.1016/j.eucr.2025.103091\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk sac tumor. Despite guideline-directed systemic chemotherapy, the course was complicated by tumor-related bleeding and venous thromboembolism, resulting in death from massive pulmonary embolism. This case highlights the aggressiveness of adult yolk sac tumors and need for early intervention.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"61 \",\"pages\":\"Article 103091\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-06-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025001627\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025001627","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Fungating extra-scrotal mass: Clinical T4 testicular cancer in a young adult
Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk sac tumor. Despite guideline-directed systemic chemotherapy, the course was complicated by tumor-related bleeding and venous thromboembolism, resulting in death from massive pulmonary embolism. This case highlights the aggressiveness of adult yolk sac tumors and need for early intervention.