ccl4诱导亚硫酸钠合成硫代膦酸盐、亚砜和砜

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2025-05-22 DOI:10.1021/acs.joc.5c0058610.1021/acs.joc.5c00586

Xiangyun Yang, Silong Chen, Nan Huang, Yanping Huo, Yang Gao, Xianwei Li and Qian Chen*,

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引用次数: 0

摘要

在温和条件下，以CCl4（1.0当量）诱导无臭的亚硫酸钠为原料，实现了无外源还原剂和无酸合成硫代膦酸盐的实验。这一转化为磷硫代酸酯的合成提供了一种高效的方法，收率高达98%，具有良好的官能团相容性。此外，还意外地以二甲基亚砜为溶剂，用ccl4诱导亚硫酸钠合成亚砜和亚砜。

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CCl4-Induced Synthesis of Phosphonothioates, Sulfoxides, and Sulfones from Sodium Sulfinates

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CCl4-Induced Synthesis of Phosphonothioates, Sulfoxides, and Sulfones from Sodium Sulfinates

An external reductant-free and acid-free synthesis of phosphonothioates from odorless sodium sulfinates induced by CCl₄ (1.0 equiv) under mild conditions has been achieved. This transformation provides an efficient synthetic approach to phosphonothioates in up to 98% yield with good functional group compatibility. In addition, an unexpected CCl₄-induced synthesis of sulfoxides and sulfones from sodium sulfinates using DMSO as the solvent has been developed.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.