{"title":"超越消灭:揭露尼泊尔远西部的麻风病病例","authors":"Smriti Lama Thing, Deepak Subedi, Anita Tamang Waiba, Neha Bista, Apsara Hamal, Monika Gurung","doi":"10.1002/ccr3.70547","DOIUrl":null,"url":null,"abstract":"<p>Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid-fast bacilli (AFB). In this article, we present two cases: a 30-year-old male misdiagnosed with <i>Tinea corporis</i> infection for a year before being correctly diagnosed with borderline tuberculoid leprosy via biopsy, and an 18-year-old male who discontinued multidrug therapy (MDT) due to stigma and later presented with a type 2 lepra reaction. These cases show hidden leprosy in Far West Nepal, highlighting the need for early diagnosis and treatment, addressing the stigmas and promoting proper knowledge, and additionally, the need to ensure a collaborative response from health workers, local government, and the community to prevent disabilities and reduce the psychological and socio-economic burden on individuals.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 6","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70547","citationCount":"0","resultStr":"{\"title\":\"Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal\",\"authors\":\"Smriti Lama Thing, Deepak Subedi, Anita Tamang Waiba, Neha Bista, Apsara Hamal, Monika Gurung\",\"doi\":\"10.1002/ccr3.70547\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid-fast bacilli (AFB). In this article, we present two cases: a 30-year-old male misdiagnosed with <i>Tinea corporis</i> infection for a year before being correctly diagnosed with borderline tuberculoid leprosy via biopsy, and an 18-year-old male who discontinued multidrug therapy (MDT) due to stigma and later presented with a type 2 lepra reaction. These cases show hidden leprosy in Far West Nepal, highlighting the need for early diagnosis and treatment, addressing the stigmas and promoting proper knowledge, and additionally, the need to ensure a collaborative response from health workers, local government, and the community to prevent disabilities and reduce the psychological and socio-economic burden on individuals.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 6\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70547\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70547\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70547","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal
Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid-fast bacilli (AFB). In this article, we present two cases: a 30-year-old male misdiagnosed with Tinea corporis infection for a year before being correctly diagnosed with borderline tuberculoid leprosy via biopsy, and an 18-year-old male who discontinued multidrug therapy (MDT) due to stigma and later presented with a type 2 lepra reaction. These cases show hidden leprosy in Far West Nepal, highlighting the need for early diagnosis and treatment, addressing the stigmas and promoting proper knowledge, and additionally, the need to ensure a collaborative response from health workers, local government, and the community to prevent disabilities and reduce the psychological and socio-economic burden on individuals.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).