Reza Ibrahimi, Farid Poursadegh, Mahnaz Mozdourian, Fariba Rezaeetalab, Zohre Emamdadi, Sahar Arab Yousefabadi, Sara Samadi
{"title":"肺诺卡菌病在免疫正常的病人:一个病例报告","authors":"Reza Ibrahimi, Farid Poursadegh, Mahnaz Mozdourian, Fariba Rezaeetalab, Zohre Emamdadi, Sahar Arab Yousefabadi, Sara Samadi","doi":"10.1002/ccr3.70505","DOIUrl":null,"url":null,"abstract":"<p>The patient, a 56-year-old female with a history of childhood bronchiectasis and controlled hypertension, presented with fever, cough, and hemoptysis. Despite initial treatment for exacerbation of bronchiectasis, her condition worsened, leading to sepsis. Blood tests revealed leukocytosis and elevated CRP. Lung HRCT showed necrotic consolidation and nodules in the left and right lung, suggestive of necrotizing pneumonia. Bronchoscopy revealed <i>Nocardia</i> species, leading to intravenous co-trimoxazole treatment. After a week in ICU, the patient improved and was discharged with oral co-trimoxazole. The patient remained free of relapse during a 6-month follow-up period, with no CNS or cutaneous involvement detected.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 6","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70505","citationCount":"0","resultStr":"{\"title\":\"Pulmonary Nocardiosis in an Immunocompetent Patient: A Case Report\",\"authors\":\"Reza Ibrahimi, Farid Poursadegh, Mahnaz Mozdourian, Fariba Rezaeetalab, Zohre Emamdadi, Sahar Arab Yousefabadi, Sara Samadi\",\"doi\":\"10.1002/ccr3.70505\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The patient, a 56-year-old female with a history of childhood bronchiectasis and controlled hypertension, presented with fever, cough, and hemoptysis. Despite initial treatment for exacerbation of bronchiectasis, her condition worsened, leading to sepsis. Blood tests revealed leukocytosis and elevated CRP. Lung HRCT showed necrotic consolidation and nodules in the left and right lung, suggestive of necrotizing pneumonia. Bronchoscopy revealed <i>Nocardia</i> species, leading to intravenous co-trimoxazole treatment. After a week in ICU, the patient improved and was discharged with oral co-trimoxazole. The patient remained free of relapse during a 6-month follow-up period, with no CNS or cutaneous involvement detected.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 6\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70505\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70505\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70505","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Pulmonary Nocardiosis in an Immunocompetent Patient: A Case Report
The patient, a 56-year-old female with a history of childhood bronchiectasis and controlled hypertension, presented with fever, cough, and hemoptysis. Despite initial treatment for exacerbation of bronchiectasis, her condition worsened, leading to sepsis. Blood tests revealed leukocytosis and elevated CRP. Lung HRCT showed necrotic consolidation and nodules in the left and right lung, suggestive of necrotizing pneumonia. Bronchoscopy revealed Nocardia species, leading to intravenous co-trimoxazole treatment. After a week in ICU, the patient improved and was discharged with oral co-trimoxazole. The patient remained free of relapse during a 6-month follow-up period, with no CNS or cutaneous involvement detected.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).