铜/双（亚胺）催化未活化烯烃的氟烷基硫氰化反应

IF 2.7 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2025-06-05 DOI:10.1002/ejoc.202500393

Leonid A. Peresypkin, Vladislav S. Kostromitin, Vitalij V. Levin, Alexander D. Dilman

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引用次数: 0

摘要

介绍了一种利用氟化卤化物和硫氰酸盐阴离子对非活化烯烃进行自由基双官能化的方法。廉价的硫氰酸铜(I)与易于获得的二（亚胺）配体的结合促进了紫光照射下的反应，而无需额外的光催化剂。该方法适用于氯氟乙酸盐和溴代氟乙酸盐以及其他氟化溴化物，并适用于各种各样的官能团。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Copper/Bis(imine)-Catalyzed Fluoroalkylative Thiocyanation of Unactivated Alkenes

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Copper/Bis(imine)-Catalyzed Fluoroalkylative Thiocyanation of Unactivated Alkenes

A method for the radical difunctionalization of nonactivated alkenes using fluorinated halides and thiocyanate anion is described. A combination of cheap copper(I) thiocyanate with a readily accessible bis(imine) ligand promoted the reaction under purple light irradiation without additional photocatalyst. The method is applicable to chloro- and bromodifluoroacetate, as well as to other fluorinated bromides, and tolerates a wide variety of functional groups.

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.